Developmental exposure to arsenic reduces anxiety levels and leads to a depressive-like behavior in female offspring rats: Molecular changes in the prefrontal cortex

Exposure to inorganic arsenic (iAs) detrimentally affects the structure and function of the central nervous system. In-utero and postnatal exposure to iAs has been connected to adverse effects on cognitive development. Therefore, this investigation explores neurobehavioral and neurochemical effects...

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Veröffentlicht in:	Neurotoxicology (Park Forest South) 2024-09, Vol.104, p.85-94
Hauptverfasser:	Bartos, Mariana, Gallegos, Cristina E., Mónaco, Nina, Lencinas, Ileana, Dominguez, Sergio, Bras, Cristina, del Carmen Esandi, María, Bouzat, Cecilia, Gumilar, Fernanda
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anxiety Anxiety - chemically induced Arsenic Arsenic - toxicity Behavior, Animal - drug effects Depression - chemically induced Depression - metabolism Depressive-like behavior Female Male Neurotoxicity Oxidative stress Oxidative Stress - drug effects Prefrontal cortex Prefrontal Cortex - drug effects Prefrontal Cortex - metabolism Pregnancy Prenatal Exposure Delayed Effects - chemically induced Rats Rats, Wistar Receptors, GABA-A - metabolism
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