Functional OmpA of Salmonella Typhimurium provides protection from lysosomal degradation and inhibits autophagic processes in macrophages

Our previous study showed that OmpA-deficient Salmonella Typhimurium (STM) failed to retain LAMP-1, quit Salmonella-containing vacuole (SCV) and escaped to the host cytosol. Here we show that the cytosolic population of STM ΔompA sequestered autophagic markers, syntaxin17 and LC3B in a sseL-dependen...

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Veröffentlicht in:	The Journal of infectious diseases 2024-07
Hauptverfasser:	Roy Chowdhury, Atish, Hajra, Dipasree, Mukherjee, Debapriya, Nair, Abhilash Vijay, Chakravortty, Dipshikha
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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