PCSK9 gene variations in the clinical setting of premature cardiovascular disease: A critical appraisal

Information about PCSK9 gene variations and its association with cardiovascular (CV) disease is controversial. We aimed to evaluate 3 reported polymorphisms in PSCK9 in a cohort of young patients with myocardial infarction with ST segment elevation (STEMI). Retrospective study of consecutive patient...

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Veröffentlicht in:	International journal of cardiology 2024-10, Vol.413, p.132402, Article 132402
Hauptverfasser:	Lorca, Rebeca, Aparicio, Andrea, Gutiérrez, Luis, Álvarez-Velasco, Rut, González-Urbistondo, Francisco, Pascual, Isaac, Gómez, Juan, Vazquez-Coto, Daniel, Garcia-Lago, Claudia, Avanzas, Pablo, Coto, Eliecer
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult CAD Cardiovascular Diseases - genetics Cohort Studies Coronary Artery Disease - diagnosis Coronary Artery Disease - genetics Female Genetic Predisposition to Disease - genetics Genetic Variation - genetics Genotype Humans Male Middle Aged PCSK9 gene Polymorphism, Single Nucleotide Prognosis Proprotein Convertase 9 - genetics Retrospective Studies Risk factors ST Elevation Myocardial Infarction - genetics
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