Plasma Kallistatin and Progranulin as Predictive Biomarkers of Intraamniotic Inflammation, Microbial Invasion of the Amniotic Cavity, and Composite Neonatal Morbidity/Mortality in Women With Preterm Premature Rupture of Membranes

ABSTRACT Problem To explore the clinical utility of nine inflammatory immune‐, adhesion‐, and extracellular matrix‐related mediators in the plasma for predicting intraamniotic inflammation and/or microbial invasion of the amniotic cavity (IAI/MIAC) and composite neonatal morbidity and/or mortality (...

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Veröffentlicht in:	American journal of reproductive immunology (1989) 2024-07, Vol.92 (1), p.e13909-n/a
Hauptverfasser:	Park, Kyo Hoon, Lee, Kyong‐No, Cho, Iseop, Lee, Min Jung, Choi, Bo Young, Jeong, Da Eun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amniocentesis Amniotic fluid Amniotic Fluid - metabolism Amniotic Fluid - microbiology Biomarkers Biomarkers - blood Chorioamnionitis - blood Chorioamnionitis - immunology composite neonatal morbidity/mortality Enzyme-linked immunosorbent assay Extracellular matrix Female Fetal Membranes, Premature Rupture - blood Gestational age Humans Infant, Newborn Inflammation Inflammation - blood Intercellular Signaling Peptides and Proteins - blood intraamniotic inflammation Leukocytes (neutrophilic) Lymphocytes microbial invasion of amniotic cavity Morbidity Mortality Neonates Plasma Plasma levels prediction model Prediction models Pregnancy preterm premature rupture of membranes Progranulins - blood Regression analysis Retrospective Studies Rupture Sampling Serpins - blood Ultrasonic imaging Ultrasound
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