Resolving the current controversy of use and reuse of housekeeping proteins in ageing research: Focus on saving people’s tax dollars

The use of housekeeping genes and proteins to normalize mRNA and protein levels in biomedical research has faced growing scrutiny. Researchers encounter challenges in determining the optimal frequency for running housekeeping proteins such as β-actin, Tubulin, and GAPDH for nuclear-encoded proteins,...

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Veröffentlicht in:	Ageing research reviews 2024-09, Vol.100, p.102437, Article 102437
Hauptverfasser:	Kshirsagar, Sudhir, Islam, Md Ariful, Reddy, Arubala P., Reddy, P. Hemachandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - genetics Aging - metabolism Animals Anonymous reader Biomedical Research - economics GAPDH Genes, Essential Housekeeping genes/proteins Humans Molecular biology Porin Protein chemistry and Academic institutions Proteins - metabolism β-actin
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