Comparison of Conventional versus Modified Preperitoneal Pelvic Packing in Patients with Bleeding Pelvic Fractures: A Single-Center Retrospective Pilot Study
: Bleeding pelvic fractures have high mortality rates, primarily due to severe hemorrhage. Treatment options include mechanical stabilization based on preperitoneal pelvic packing (PPP), resuscitative endovascular balloon occlusion of the aorta, and angioembolization (AE). The bilateral preperitonea...
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Veröffentlicht in: | Journal of clinical medicine 2024-07, Vol.13 (14), p.4062 |
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description | : Bleeding pelvic fractures have high mortality rates, primarily due to severe hemorrhage. Treatment options include mechanical stabilization based on preperitoneal pelvic packing (PPP), resuscitative endovascular balloon occlusion of the aorta, and angioembolization (AE). The bilateral preperitoneal approach, which uses three pads on each side, is the conventional PPP method. We aimed to compare the bilateral preperitoneal approach with a modified approach, involving selectively packing only heavily bleeding areas, in terms of clinical outcomes and mortality risks.
We included patients who underwent PPP and compared the outcomes between conventional (three sponges placed on each side) and modified PPP (selective packing of critical areas). The primary outcome was 30-day mortality; the secondary outcomes included 24 h mortality, pelvic complications, and transfusion requirements. Univariate and multivariate analyses were performed to determine risk factors for 30-day and 24 h mortality.
Among the 47 included patients, 19 and 28 underwent conventional and modified PPP, respectively. There were no significant between-group differences in the 24 h (26.3% vs. 42.9%,
= 0.247) and 30-day mortality rates (47.4% vs. 60.7%,
= 0.366). Using univariate and multivariate analyses, initial lactate levels and the decision to perform AE were found to be significant risk factors for mortality. However, the selected PPP method was not a risk factor for 30-day mortality (odds ratio [OR], 2.22; 95% confidence interval [CI], 0.27-18.26;
= 0.457) or 24 hr mortality (OR, 1.77; 95% CI, 0.24-13.19;
= 0.557).
The modified PPP method may be considered in patients with bleeding pelvic fractures for effective bleeding control while minimizing potential complications associated with the conventional PPP. |
doi_str_mv | 10.3390/jcm13144062 |
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We included patients who underwent PPP and compared the outcomes between conventional (three sponges placed on each side) and modified PPP (selective packing of critical areas). The primary outcome was 30-day mortality; the secondary outcomes included 24 h mortality, pelvic complications, and transfusion requirements. Univariate and multivariate analyses were performed to determine risk factors for 30-day and 24 h mortality.
Among the 47 included patients, 19 and 28 underwent conventional and modified PPP, respectively. There were no significant between-group differences in the 24 h (26.3% vs. 42.9%,
= 0.247) and 30-day mortality rates (47.4% vs. 60.7%,
= 0.366). Using univariate and multivariate analyses, initial lactate levels and the decision to perform AE were found to be significant risk factors for mortality. However, the selected PPP method was not a risk factor for 30-day mortality (odds ratio [OR], 2.22; 95% confidence interval [CI], 0.27-18.26;
= 0.457) or 24 hr mortality (OR, 1.77; 95% CI, 0.24-13.19;
= 0.557).
The modified PPP method may be considered in patients with bleeding pelvic fractures for effective bleeding control while minimizing potential complications associated with the conventional PPP.</description><identifier>ISSN: 2077-0383</identifier><identifier>EISSN: 2077-0383</identifier><identifier>DOI: 10.3390/jcm13144062</identifier><identifier>PMID: 39064102</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Blood ; Emergency medical care ; Hemorrhage ; Injuries ; Mortality ; Multivariate analysis ; Nonparametric statistics ; Packaging ; Patients ; Pneumonia ; Risk factors ; Surgical site infections ; Trauma ; Urinary tract diseases ; Urinary tract infections ; Urogenital system</subject><ispartof>Journal of clinical medicine, 2024-07, Vol.13 (14), p.4062</ispartof><rights>2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c242t-83e7f0143aa5a1babf253f61561a427b747789404537be82ee3ecf2c1608658c3</cites><orcidid>0000-0002-7943-5933 ; 0000-0002-8906-4312 ; 0000-0002-2444-2343</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39064102$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jeon, Sebeom</creatorcontrib><creatorcontrib>Yu, Byungchul</creatorcontrib><creatorcontrib>Lee, Gil Jae</creatorcontrib><creatorcontrib>Lee, Min A</creatorcontrib><creatorcontrib>Lee, Jungnam</creatorcontrib><creatorcontrib>Choi, Kang Kook</creatorcontrib><title>Comparison of Conventional versus Modified Preperitoneal Pelvic Packing in Patients with Bleeding Pelvic Fractures: A Single-Center Retrospective Pilot Study</title><title>Journal of clinical medicine</title><addtitle>J Clin Med</addtitle><description>: Bleeding pelvic fractures have high mortality rates, primarily due to severe hemorrhage. Treatment options include mechanical stabilization based on preperitoneal pelvic packing (PPP), resuscitative endovascular balloon occlusion of the aorta, and angioembolization (AE). The bilateral preperitoneal approach, which uses three pads on each side, is the conventional PPP method. We aimed to compare the bilateral preperitoneal approach with a modified approach, involving selectively packing only heavily bleeding areas, in terms of clinical outcomes and mortality risks.
We included patients who underwent PPP and compared the outcomes between conventional (three sponges placed on each side) and modified PPP (selective packing of critical areas). The primary outcome was 30-day mortality; the secondary outcomes included 24 h mortality, pelvic complications, and transfusion requirements. Univariate and multivariate analyses were performed to determine risk factors for 30-day and 24 h mortality.
Among the 47 included patients, 19 and 28 underwent conventional and modified PPP, respectively. There were no significant between-group differences in the 24 h (26.3% vs. 42.9%,
= 0.247) and 30-day mortality rates (47.4% vs. 60.7%,
= 0.366). Using univariate and multivariate analyses, initial lactate levels and the decision to perform AE were found to be significant risk factors for mortality. However, the selected PPP method was not a risk factor for 30-day mortality (odds ratio [OR], 2.22; 95% confidence interval [CI], 0.27-18.26;
= 0.457) or 24 hr mortality (OR, 1.77; 95% CI, 0.24-13.19;
= 0.557).
The modified PPP method may be considered in patients with bleeding pelvic fractures for effective bleeding control while minimizing potential complications associated with the conventional PPP.</description><subject>Blood</subject><subject>Emergency medical care</subject><subject>Hemorrhage</subject><subject>Injuries</subject><subject>Mortality</subject><subject>Multivariate analysis</subject><subject>Nonparametric statistics</subject><subject>Packaging</subject><subject>Patients</subject><subject>Pneumonia</subject><subject>Risk factors</subject><subject>Surgical site infections</subject><subject>Trauma</subject><subject>Urinary tract diseases</subject><subject>Urinary tract infections</subject><subject>Urogenital system</subject><issn>2077-0383</issn><issn>2077-0383</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkU1P3DAQhi3UqiDYU-_IEpdKVcBfib3caFQ-JBArlp4jx5m0XpI4tZ1F_Jj-V7xlQYi5zEjv84408yL0lZJjzufkZGV6yqkQpGA7aI8RKTPCFf_0bt5FsxBWJJVSglH5Be0mZyEoYXvoX-n6UXsb3IBdi0s3rGGI1g26w2vwYQr4xjW2tdDghYcRvI1ugKQuoFtbgxfaPNjhN7ZDGqNN5oAfbfyDf3QAzUbZgudemzh5CKf4DC-T0EFWJhw8voPoXRjBRLsGvLCdi3gZp-bpAH1udRdgtu376Nf5z_vyMru-vbgqz64zwwSLmeIgW0IF1zrXtNZ1y3LeFjQvqBZM1lJIqeaCiJzLGhQD4GBaZmhBVJErw_fRt5e9o3d_Jwix6m0w0HV6ADeFihOVUzonQib06AO6cpNP7_pPiTmTlG6o7y-USYcFD201ettr_1RRUm2Cq94Fl-jD7c6p7qF5Y19j4s9MAZRo</recordid><startdate>20240711</startdate><enddate>20240711</enddate><creator>Jeon, Sebeom</creator><creator>Yu, Byungchul</creator><creator>Lee, Gil Jae</creator><creator>Lee, Min A</creator><creator>Lee, Jungnam</creator><creator>Choi, Kang Kook</creator><general>MDPI AG</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-7943-5933</orcidid><orcidid>https://orcid.org/0000-0002-8906-4312</orcidid><orcidid>https://orcid.org/0000-0002-2444-2343</orcidid></search><sort><creationdate>20240711</creationdate><title>Comparison of Conventional versus Modified Preperitoneal Pelvic Packing in Patients with Bleeding Pelvic Fractures: A Single-Center Retrospective Pilot Study</title><author>Jeon, Sebeom ; Yu, Byungchul ; Lee, Gil Jae ; Lee, Min A ; Lee, Jungnam ; Choi, Kang Kook</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c242t-83e7f0143aa5a1babf253f61561a427b747789404537be82ee3ecf2c1608658c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Blood</topic><topic>Emergency medical care</topic><topic>Hemorrhage</topic><topic>Injuries</topic><topic>Mortality</topic><topic>Multivariate analysis</topic><topic>Nonparametric statistics</topic><topic>Packaging</topic><topic>Patients</topic><topic>Pneumonia</topic><topic>Risk factors</topic><topic>Surgical site infections</topic><topic>Trauma</topic><topic>Urinary tract diseases</topic><topic>Urinary tract infections</topic><topic>Urogenital system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jeon, Sebeom</creatorcontrib><creatorcontrib>Yu, Byungchul</creatorcontrib><creatorcontrib>Lee, Gil Jae</creatorcontrib><creatorcontrib>Lee, Min A</creatorcontrib><creatorcontrib>Lee, Jungnam</creatorcontrib><creatorcontrib>Choi, Kang Kook</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jeon, Sebeom</au><au>Yu, Byungchul</au><au>Lee, Gil Jae</au><au>Lee, Min A</au><au>Lee, Jungnam</au><au>Choi, Kang Kook</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of Conventional versus Modified Preperitoneal Pelvic Packing in Patients with Bleeding Pelvic Fractures: A Single-Center Retrospective Pilot Study</atitle><jtitle>Journal of clinical medicine</jtitle><addtitle>J Clin Med</addtitle><date>2024-07-11</date><risdate>2024</risdate><volume>13</volume><issue>14</issue><spage>4062</spage><pages>4062-</pages><issn>2077-0383</issn><eissn>2077-0383</eissn><abstract>: Bleeding pelvic fractures have high mortality rates, primarily due to severe hemorrhage. Treatment options include mechanical stabilization based on preperitoneal pelvic packing (PPP), resuscitative endovascular balloon occlusion of the aorta, and angioembolization (AE). The bilateral preperitoneal approach, which uses three pads on each side, is the conventional PPP method. We aimed to compare the bilateral preperitoneal approach with a modified approach, involving selectively packing only heavily bleeding areas, in terms of clinical outcomes and mortality risks.
We included patients who underwent PPP and compared the outcomes between conventional (three sponges placed on each side) and modified PPP (selective packing of critical areas). The primary outcome was 30-day mortality; the secondary outcomes included 24 h mortality, pelvic complications, and transfusion requirements. Univariate and multivariate analyses were performed to determine risk factors for 30-day and 24 h mortality.
Among the 47 included patients, 19 and 28 underwent conventional and modified PPP, respectively. There were no significant between-group differences in the 24 h (26.3% vs. 42.9%,
= 0.247) and 30-day mortality rates (47.4% vs. 60.7%,
= 0.366). Using univariate and multivariate analyses, initial lactate levels and the decision to perform AE were found to be significant risk factors for mortality. However, the selected PPP method was not a risk factor for 30-day mortality (odds ratio [OR], 2.22; 95% confidence interval [CI], 0.27-18.26;
= 0.457) or 24 hr mortality (OR, 1.77; 95% CI, 0.24-13.19;
= 0.557).
The modified PPP method may be considered in patients with bleeding pelvic fractures for effective bleeding control while minimizing potential complications associated with the conventional PPP.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>39064102</pmid><doi>10.3390/jcm13144062</doi><orcidid>https://orcid.org/0000-0002-7943-5933</orcidid><orcidid>https://orcid.org/0000-0002-8906-4312</orcidid><orcidid>https://orcid.org/0000-0002-2444-2343</orcidid><oa>free_for_read</oa></addata></record> |
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source | PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; EZB-FREE-00999 freely available EZB journals; PubMed Central |
subjects | Blood Emergency medical care Hemorrhage Injuries Mortality Multivariate analysis Nonparametric statistics Packaging Patients Pneumonia Risk factors Surgical site infections Trauma Urinary tract diseases Urinary tract infections Urogenital system |
title | Comparison of Conventional versus Modified Preperitoneal Pelvic Packing in Patients with Bleeding Pelvic Fractures: A Single-Center Retrospective Pilot Study |
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