Comparison of clot waveform analysis with or without adjustment between prothrombin time and activated partial thromboplastin time assays to assess in vitro effects of direct oral anticoagulants

•Clot waveform analysis enhances the interpretation of clotting time measurement.•Clot waveform analysis is adjusted to compensate the influence of fibrinogen.•Clot waveform analysis in PT and APTT assays was done for DOAC-spiked plasma.•Distinct features of DOAC effects were revealed in extrinsic a...

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Veröffentlicht in:Clinica chimica acta 2024-08, Vol.562, p.119887, Article 119887
Hauptverfasser: Wakui, Masatoshi, Fujimori, Yuta, Ozaki, Yuko, Oka, Shusaku, Ziparo, Maria, Osada, Emiri, Kondo, Yoshino, Nakagawa, Terumichi, Nakamura, Shoko, Matsushita, Hiromichi
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