A metabolic balance of GLP-1 and NMDA receptors in the brain

Glucagon-like peptide-1 (GLP-1) and N-methyl-D-aspartate (NMDA) receptors in the brain regulate metabolic homeostasis. In a paper published in Nature, Petersen et al. describe a bimodal molecule that conjugates a GLP-1 analog with MK-801 (NMDA receptor antagonist), which lowers feeding and body weig...

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Veröffentlicht in:	Cell 2024-07, Vol.187 (15), p.3854-3856
Hauptverfasser:	Yue, Jessica T.Y., Garrido, Ameth N., Lam, Tony K.T.
Format:	Artikel
Sprache:	eng
Schlagworte:	agonists Animals antagonists body weight brain Brain - metabolism Dizocilpine Maleate - pharmacology glucagon-like peptide 1 Glucagon-Like Peptide 1 - metabolism Glucagon-Like Peptide-1 Receptor - agonists Glucagon-Like Peptide-1 Receptor - metabolism homeostasis Humans Receptors, N-Methyl-D-Aspartate - metabolism
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