Effectiveness of Treatment Approaches in COVID-19 Pneumonia: A Comparative Evaluation between a Specialized Center and Conventional Hospitals
The early stages of the COVID-19 pandemic overwhelmed general hospitals in Spain. In response, a dedicated hospital for COVID-19 care, the Hospital de Emergencias Enfermera Isabel Zendal (HEEIZ), was established. This study aimed to compare clinical outcomes of COVID-19 patients treated at the speci...
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| Veröffentlicht in: | Healthcare (Basel) 2024-07, Vol.12 (14), p.1365 |
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| creator | Romero Pareja, Rodolfo Ruiz Grinspan, Martín S Castro Arias, María Lorena García Hernández, Raquel Martín Sánchez, Francisco Javier Álvarez-Rodríguez, Esther Álvarez Rodríguez, Virginia Minguens, Iria Martínez Molina, Ana María Torres Santos-Olmo, Rosario Aranda, Sixto Torres Rodríguez, Enrique Gimeno Galindo, Carmen Thuissard-Vasallo, Israel J Marco Martínez, Javier |
| description | The early stages of the COVID-19 pandemic overwhelmed general hospitals in Spain. In response, a dedicated hospital for COVID-19 care, the Hospital de Emergencias Enfermera Isabel Zendal (HEEIZ), was established. This study aimed to compare clinical outcomes of COVID-19 patients treated at the specialized HEEIZ with those at conventional general hospitals (CGHs) in Madrid, Spain.
The study was a prospective, observational cohort study including COVID-19 patients admitted to the HEEIZ and 14 CGHs (December 2020 to August 2021). Patients were assigned based on hospital preference. Clinical data were collected and analyzed using multivariate regression to assess primary and secondary outcomes, including hospital mortality, need of invasive mechanical ventilation (IMV), and pharmacological treatments.
The HEEIZ cohort (
= 2997) was younger and had lower Charlson comorbidity scores than the CGH cohort (
= 1526). Adjusted HEEIZ hospital mortality was not significantly higher compared with CGHs (OR: 1.274; 95% CI: 0.781-2.079;
= 0.332).
During the study period, patients admitted to the HEEIZ showed no significant differences in clinical outcomes, compared with patients admitted at CGHs. These results might support the use of specialized centers in managing pandemic surges, allowing CGHs to handle other needs. |
| doi_str_mv | 10.3390/healthcare12141365 |
| format | Article |
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The study was a prospective, observational cohort study including COVID-19 patients admitted to the HEEIZ and 14 CGHs (December 2020 to August 2021). Patients were assigned based on hospital preference. Clinical data were collected and analyzed using multivariate regression to assess primary and secondary outcomes, including hospital mortality, need of invasive mechanical ventilation (IMV), and pharmacological treatments.
The HEEIZ cohort (
= 2997) was younger and had lower Charlson comorbidity scores than the CGH cohort (
= 1526). Adjusted HEEIZ hospital mortality was not significantly higher compared with CGHs (OR: 1.274; 95% CI: 0.781-2.079;
= 0.332).
During the study period, patients admitted to the HEEIZ showed no significant differences in clinical outcomes, compared with patients admitted at CGHs. These results might support the use of specialized centers in managing pandemic surges, allowing CGHs to handle other needs.</description><identifier>ISSN: 2227-9032</identifier><identifier>EISSN: 2227-9032</identifier><identifier>DOI: 10.3390/healthcare12141365</identifier><identifier>PMID: 39057508</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Bacterial pneumonia ; Care and treatment ; Central service department ; Chronic obstructive pulmonary disease ; Coronaviruses ; COVID-19 ; Demographics ; Emergency medical care ; Health facilities ; Hospitals ; Infectious diseases ; Intensive care ; Mortality ; Pandemics ; Patient admissions ; Patient outcomes ; Pneumonia ; Respiratory failure ; Ventilators</subject><ispartof>Healthcare (Basel), 2024-07, Vol.12 (14), p.1365</ispartof><rights>COPYRIGHT 2024 MDPI AG</rights><rights>2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c323t-72d7967ad81716145031b0eb5e4d859115a990756b75cfa51b53f359b14ef26a3</cites><orcidid>0000-0002-6596-9299 ; 0000-0002-7342-9110 ; 0000-0002-3777-2050 ; 0000-0002-6990-0619 ; 0000-0003-1692-3179</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39057508$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Romero Pareja, Rodolfo</creatorcontrib><creatorcontrib>Ruiz Grinspan, Martín S</creatorcontrib><creatorcontrib>Castro Arias, María Lorena</creatorcontrib><creatorcontrib>García Hernández, Raquel</creatorcontrib><creatorcontrib>Martín Sánchez, Francisco Javier</creatorcontrib><creatorcontrib>Álvarez-Rodríguez, Esther</creatorcontrib><creatorcontrib>Álvarez Rodríguez, Virginia</creatorcontrib><creatorcontrib>Minguens, Iria</creatorcontrib><creatorcontrib>Martínez Molina, Ana María</creatorcontrib><creatorcontrib>Torres Santos-Olmo, Rosario</creatorcontrib><creatorcontrib>Aranda, Sixto</creatorcontrib><creatorcontrib>Torres Rodríguez, Enrique</creatorcontrib><creatorcontrib>Gimeno Galindo, Carmen</creatorcontrib><creatorcontrib>Thuissard-Vasallo, Israel J</creatorcontrib><creatorcontrib>Marco Martínez, Javier</creatorcontrib><title>Effectiveness of Treatment Approaches in COVID-19 Pneumonia: A Comparative Evaluation between a Specialized Center and Conventional Hospitals</title><title>Healthcare (Basel)</title><addtitle>Healthcare (Basel)</addtitle><description>The early stages of the COVID-19 pandemic overwhelmed general hospitals in Spain. In response, a dedicated hospital for COVID-19 care, the Hospital de Emergencias Enfermera Isabel Zendal (HEEIZ), was established. This study aimed to compare clinical outcomes of COVID-19 patients treated at the specialized HEEIZ with those at conventional general hospitals (CGHs) in Madrid, Spain.
The study was a prospective, observational cohort study including COVID-19 patients admitted to the HEEIZ and 14 CGHs (December 2020 to August 2021). Patients were assigned based on hospital preference. Clinical data were collected and analyzed using multivariate regression to assess primary and secondary outcomes, including hospital mortality, need of invasive mechanical ventilation (IMV), and pharmacological treatments.
The HEEIZ cohort (
= 2997) was younger and had lower Charlson comorbidity scores than the CGH cohort (
= 1526). Adjusted HEEIZ hospital mortality was not significantly higher compared with CGHs (OR: 1.274; 95% CI: 0.781-2.079;
= 0.332).
During the study period, patients admitted to the HEEIZ showed no significant differences in clinical outcomes, compared with patients admitted at CGHs. These results might support the use of specialized centers in managing pandemic surges, allowing CGHs to handle other needs.</description><subject>Bacterial pneumonia</subject><subject>Care and treatment</subject><subject>Central service department</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>Demographics</subject><subject>Emergency medical care</subject><subject>Health facilities</subject><subject>Hospitals</subject><subject>Infectious diseases</subject><subject>Intensive care</subject><subject>Mortality</subject><subject>Pandemics</subject><subject>Patient admissions</subject><subject>Patient outcomes</subject><subject>Pneumonia</subject><subject>Respiratory 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(Basel)</jtitle><addtitle>Healthcare (Basel)</addtitle><date>2024-07-09</date><risdate>2024</risdate><volume>12</volume><issue>14</issue><spage>1365</spage><pages>1365-</pages><issn>2227-9032</issn><eissn>2227-9032</eissn><abstract>The early stages of the COVID-19 pandemic overwhelmed general hospitals in Spain. In response, a dedicated hospital for COVID-19 care, the Hospital de Emergencias Enfermera Isabel Zendal (HEEIZ), was established. This study aimed to compare clinical outcomes of COVID-19 patients treated at the specialized HEEIZ with those at conventional general hospitals (CGHs) in Madrid, Spain.
The study was a prospective, observational cohort study including COVID-19 patients admitted to the HEEIZ and 14 CGHs (December 2020 to August 2021). Patients were assigned based on hospital preference. Clinical data were collected and analyzed using multivariate regression to assess primary and secondary outcomes, including hospital mortality, need of invasive mechanical ventilation (IMV), and pharmacological treatments.
The HEEIZ cohort (
= 2997) was younger and had lower Charlson comorbidity scores than the CGH cohort (
= 1526). Adjusted HEEIZ hospital mortality was not significantly higher compared with CGHs (OR: 1.274; 95% CI: 0.781-2.079;
= 0.332).
During the study period, patients admitted to the HEEIZ showed no significant differences in clinical outcomes, compared with patients admitted at CGHs. These results might support the use of specialized centers in managing pandemic surges, allowing CGHs to handle other needs.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>39057508</pmid><doi>10.3390/healthcare12141365</doi><orcidid>https://orcid.org/0000-0002-6596-9299</orcidid><orcidid>https://orcid.org/0000-0002-7342-9110</orcidid><orcidid>https://orcid.org/0000-0002-3777-2050</orcidid><orcidid>https://orcid.org/0000-0002-6990-0619</orcidid><orcidid>https://orcid.org/0000-0003-1692-3179</orcidid><oa>free_for_read</oa></addata></record> |
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| source | MDPI - Multidisciplinary Digital Publishing Institute; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access |
| subjects | Bacterial pneumonia Care and treatment Central service department Chronic obstructive pulmonary disease Coronaviruses COVID-19 Demographics Emergency medical care Health facilities Hospitals Infectious diseases Intensive care Mortality Pandemics Patient admissions Patient outcomes Pneumonia Respiratory failure Ventilators |
| title | Effectiveness of Treatment Approaches in COVID-19 Pneumonia: A Comparative Evaluation between a Specialized Center and Conventional Hospitals |
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