Genotoxicity and cytotoxicity evaluation of a heat-not-burn product

‘Heat-not-burn’ products (HnBP) contain lower levels of harmful substances than traditional cigarettes, but the use of these products warrants further toxicological evaluation. We have compared the cytotoxicity and genotoxicity of a heat-not burn product with conventional cigarettes, in vivo and in...

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Veröffentlicht in:	Mutation research. Genetic toxicology and environmental mutagenesis 2024-07, Vol.897, p.503784, Article 503784
Hauptverfasser:	Fu, Fudong, Li, Xiaoyu, Chen, Younan, Li, Lan, Dou, Jiexiong, Liang, Kun, Chen, Yexian, Lu, Yanrong, Huang, Yuchuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Ames assay Animals Chromosome aberration assay Chromosome Aberrations - drug effects Comet Assay Cricetinae Cricetulus DNA Damage - drug effects Fibroblasts - drug effects Hot Temperature Male Micronucleus Tests Mutagenicity Tests Particulate Matter - toxicity Rats Rats, Sprague-Dawley Smoke - adverse effects Testis - drug effects Testis - pathology Tobacco Products - toxicity Total particulate matter
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