Conversion of 5α-Androstane-3α,17β-diol to bis(4-dimethylamino)phenyl carbamate derivative for sensitive determination of its rat brain level by LC/ESI-MS/MS

5α-Androstane-3α,17β-diol (3α,5α-Adiol) is a testosterone-derived neurosteroid and has anxiolytic and analgesic effects via γ-aminobutyric acid type A receptors as with the progesterone-derived neurosteroid, allopregnanolone (AP). Although the psychotropic drug-evoked changes in the brain AP concent...

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Veröffentlicht in:	Rapid communications in mass spectrometry 2024-10, Vol.38 (19), p.e9875
Hauptverfasser:	Higashi, Tatsuya, Tanaka, Asuka, Tsubura, Shiho, Nishimoto-Kusunose, Shoichi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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