Condensin I folds the Caenorhabditis elegans genome

The structural maintenance of chromosome (SMC) complexes—cohesin and condensins—are crucial for chromosome separation and compaction during cell division. During the interphase, mammalian cohesins additionally fold the genome into loops and domains. Here we show that, in Caenorhabditis elegans , a s...

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Veröffentlicht in:	Nature genetics 2024-08, Vol.56 (8), p.1737-1749
Hauptverfasser:	Das, Moushumi, Semple, Jennifer I., Haemmerli, Anja, Volodkina, Valeriia, Scotton, Janik, Gitchev, Todor, Annan, Ahrmad, Campos, Julie, Statzer, Cyril, Dakhovnik, Alexander, Ewald, Collin Y., Mozziconacci, Julien, Meister, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/177 631/208/200 631/601/1737 Adenosine Triphosphatases - genetics Adenosine Triphosphatases - metabolism Agriculture Animal Genetics and Genomics Animals Binding sites Biomedical and Life Sciences Biomedicine Caenorhabditis elegans - genetics Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism Cancer Research Cell cycle Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Cell division Chromosomal Proteins, Non-Histone - genetics Chromosomal Proteins, Non-Histone - metabolism Chromosomes Chromosomes - genetics Cohesin Cohesins Cohesion Condensin DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Gene expression Gene Function Genes, X-Linked Genome, Helminth Genomes Human Genetics Inactivation Insects Interphase Interphase - genetics Mammals Multiprotein Complexes - genetics Multiprotein Complexes - metabolism Nematodes Ribosomal DNA X Chromosome - genetics X chromosomes
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