The miR172/TOE3 module regulates resistance to tobacco mosaic virus in tobacco
SUMMARY The outcome of certain plant–virus interaction is symptom recovery, which is accompanied with the emergence of asymptomatic tissues in which the virus accumulation decreased dramatically. This phenomenon shows the potential to reveal critical molecular factors for controlling viral disease....
Gespeichert in:
| Veröffentlicht in: | The Plant journal : for cell and molecular biology 2024-09, Vol.119 (6), p.2672-2686 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2686 |
|---|---|
| container_issue | 6 |
| container_start_page | 2672 |
| container_title | The Plant journal : for cell and molecular biology |
| container_volume | 119 |
| creator | Jiao, Bolei Peng, Qiding Wu, Baijun Liu, Sucen Zhou, Jingya Yuan, Bowen Lin, Honghui Xi, Dehui |
| description | SUMMARY
The outcome of certain plant–virus interaction is symptom recovery, which is accompanied with the emergence of asymptomatic tissues in which the virus accumulation decreased dramatically. This phenomenon shows the potential to reveal critical molecular factors for controlling viral disease. MicroRNAs act as master regulators in plant growth, development, and immunity. However, the mechanism by which miRNA participates in regulating symptom recovery remains largely unknown. Here, we reported that miR172 was scavenged in the recovered tissue of tobacco mosaic virus (TMV)‐infected Nicotiana tabacum plants. Overexpression of miR172 promoted TMV infection, whereas silencing of miR172 inhibited TMV infection. Then, TARGET OF EAT3 (TOE3), an APETALA2 transcription factor, was identified as a downstream target of miR172. Overexpression of NtTOE3 significantly improved plant resistance to TMV infection, while knockout of NtTOE3 facilitated virus infection. Furthermore, transcriptome analysis indicated that TOE3 promoted the expression of defense‐related genes, such as KL1 and MLP43. Overexpression of these genes conferred resistance of plant against TMV infection. Importantly, results of dual‐luciferase assay, chromatin immunoprecipitation‐quantitative PCR, and electrophoretic mobility shift assay proved that TOE3 activated the transcription of KL1 and MLP43 by binding their promoters. Moreover, overexpression of rTOE3 (the miR172‐resistant form of TOE3) significantly reduced TMV accumulation compared to the overexpression of TOE3 (the normal form of TOE3) in miR172 overexpressing Nicotiana benthamiana plants. Taken together, our study reveals the pivotal role of miR172/TOE3 module in regulating plant immunity and in the establishment of recovery in virus‐infected tobacco plants, elucidating a regulatory mechanism integrating plant growth, development, and immune response.
Significance Statement
miR172/TOE3 module is well‐known for its role in regulating reproductive process. In this study, we demonstrated that miR172/TOE3 module plays an important role in regulating the resistance of tobacco to TMV infection and the formation of symptom recovery. |
| doi_str_mv | 10.1111/tpj.16941 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3083679747</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3154184774</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2761-cf66c6d58c31f033e6225c9f14768c5f42747c035bf283bfb8d6ee80f0fa51fc3</originalsourceid><addsrcrecordid>eNqF0U1LwzAYB_AgipvTg19ACl70UJcnr-1RxnxjOJEK3kqbJtrRrjNplX17o908CGIIJIQf_4fwR-gY8AX4NW5XiwsQMYMdNAQqeEiBPu-iIY4FDiUDMkAHzi0wBkkF20cDGmOGMeZDdJ-86qAuH0GScTKf0qBuiq7SgdUvXZW12vmbK12bLZUO2sbvPFOq8cxlpQreS9u5oFxu3w_Rnskqp4825wg9XU2TyU04m1_fTi5noSJSQKiMEEoUPFIUDKZUC0K4ig0wKSLFDSOSSYUpzw2JaG7yqBBaR9hgk3Ewio7QWZ-7ss1bp12b1qVTuqqypW46l1LgDCImJfuf4ogKGfuBnp7-ooums0v_ER9IIhCcyNir814p2zhntUlXtqwzu04Bp199pL6P9LsPb082iV1e6-JHbgvwYNyDj7LS67-T0uThro_8BNLMkfk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3128165279</pqid></control><display><type>article</type><title>The miR172/TOE3 module regulates resistance to tobacco mosaic virus in tobacco</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Jiao, Bolei ; Peng, Qiding ; Wu, Baijun ; Liu, Sucen ; Zhou, Jingya ; Yuan, Bowen ; Lin, Honghui ; Xi, Dehui</creator><creatorcontrib>Jiao, Bolei ; Peng, Qiding ; Wu, Baijun ; Liu, Sucen ; Zhou, Jingya ; Yuan, Bowen ; Lin, Honghui ; Xi, Dehui</creatorcontrib><description>SUMMARY
The outcome of certain plant–virus interaction is symptom recovery, which is accompanied with the emergence of asymptomatic tissues in which the virus accumulation decreased dramatically. This phenomenon shows the potential to reveal critical molecular factors for controlling viral disease. MicroRNAs act as master regulators in plant growth, development, and immunity. However, the mechanism by which miRNA participates in regulating symptom recovery remains largely unknown. Here, we reported that miR172 was scavenged in the recovered tissue of tobacco mosaic virus (TMV)‐infected Nicotiana tabacum plants. Overexpression of miR172 promoted TMV infection, whereas silencing of miR172 inhibited TMV infection. Then, TARGET OF EAT3 (TOE3), an APETALA2 transcription factor, was identified as a downstream target of miR172. Overexpression of NtTOE3 significantly improved plant resistance to TMV infection, while knockout of NtTOE3 facilitated virus infection. Furthermore, transcriptome analysis indicated that TOE3 promoted the expression of defense‐related genes, such as KL1 and MLP43. Overexpression of these genes conferred resistance of plant against TMV infection. Importantly, results of dual‐luciferase assay, chromatin immunoprecipitation‐quantitative PCR, and electrophoretic mobility shift assay proved that TOE3 activated the transcription of KL1 and MLP43 by binding their promoters. Moreover, overexpression of rTOE3 (the miR172‐resistant form of TOE3) significantly reduced TMV accumulation compared to the overexpression of TOE3 (the normal form of TOE3) in miR172 overexpressing Nicotiana benthamiana plants. Taken together, our study reveals the pivotal role of miR172/TOE3 module in regulating plant immunity and in the establishment of recovery in virus‐infected tobacco plants, elucidating a regulatory mechanism integrating plant growth, development, and immune response.
Significance Statement
miR172/TOE3 module is well‐known for its role in regulating reproductive process. In this study, we demonstrated that miR172/TOE3 module plays an important role in regulating the resistance of tobacco to TMV infection and the formation of symptom recovery.</description><identifier>ISSN: 0960-7412</identifier><identifier>ISSN: 1365-313X</identifier><identifier>EISSN: 1365-313X</identifier><identifier>DOI: 10.1111/tpj.16941</identifier><identifier>PMID: 39040005</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Bioaccumulation ; Canonical forms ; Chromatin ; defense‐related gene ; Disease control ; Disease resistance ; Disease Resistance - genetics ; Electrophoretic mobility ; gel electrophoresis ; Gene Expression Regulation, Plant ; Genes ; Immune response ; Immune system ; Immunoprecipitation ; Infections ; microRNA ; MicroRNAs ; MicroRNAs - genetics ; MicroRNAs - metabolism ; miR172/TOE3 ; miRNA ; Modules ; Nicotiana - genetics ; Nicotiana - immunology ; Nicotiana - virology ; Nicotiana benthamiana ; Nicotiana tabacum ; Plant Diseases - genetics ; Plant Diseases - immunology ; Plant Diseases - virology ; Plant growth ; Plant immunity ; Plant layout ; Plant Proteins - genetics ; Plant Proteins - metabolism ; Plant resistance ; Plant virus diseases ; Plant viruses ; Plants, Genetically Modified ; Recovery ; Regulatory mechanisms (biology) ; symptom recovery ; Tobacco ; Tobacco mosaic virus ; Tobacco Mosaic Virus - physiology ; Tobamovirus ; transcription factors ; Transcription Factors - genetics ; Transcription Factors - metabolism ; Transcriptomes ; transcriptomics ; Viral diseases ; Viruses</subject><ispartof>The Plant journal : for cell and molecular biology, 2024-09, Vol.119 (6), p.2672-2686</ispartof><rights>2024 Society for Experimental Biology and John Wiley & Sons Ltd.</rights><rights>Copyright © 2024 Society for Experimental Biology and John Wiley & Sons Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c2761-cf66c6d58c31f033e6225c9f14768c5f42747c035bf283bfb8d6ee80f0fa51fc3</cites><orcidid>0000-0002-1314-1262</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Ftpj.16941$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Ftpj.16941$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39040005$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jiao, Bolei</creatorcontrib><creatorcontrib>Peng, Qiding</creatorcontrib><creatorcontrib>Wu, Baijun</creatorcontrib><creatorcontrib>Liu, Sucen</creatorcontrib><creatorcontrib>Zhou, Jingya</creatorcontrib><creatorcontrib>Yuan, Bowen</creatorcontrib><creatorcontrib>Lin, Honghui</creatorcontrib><creatorcontrib>Xi, Dehui</creatorcontrib><title>The miR172/TOE3 module regulates resistance to tobacco mosaic virus in tobacco</title><title>The Plant journal : for cell and molecular biology</title><addtitle>Plant J</addtitle><description>SUMMARY
The outcome of certain plant–virus interaction is symptom recovery, which is accompanied with the emergence of asymptomatic tissues in which the virus accumulation decreased dramatically. This phenomenon shows the potential to reveal critical molecular factors for controlling viral disease. MicroRNAs act as master regulators in plant growth, development, and immunity. However, the mechanism by which miRNA participates in regulating symptom recovery remains largely unknown. Here, we reported that miR172 was scavenged in the recovered tissue of tobacco mosaic virus (TMV)‐infected Nicotiana tabacum plants. Overexpression of miR172 promoted TMV infection, whereas silencing of miR172 inhibited TMV infection. Then, TARGET OF EAT3 (TOE3), an APETALA2 transcription factor, was identified as a downstream target of miR172. Overexpression of NtTOE3 significantly improved plant resistance to TMV infection, while knockout of NtTOE3 facilitated virus infection. Furthermore, transcriptome analysis indicated that TOE3 promoted the expression of defense‐related genes, such as KL1 and MLP43. Overexpression of these genes conferred resistance of plant against TMV infection. Importantly, results of dual‐luciferase assay, chromatin immunoprecipitation‐quantitative PCR, and electrophoretic mobility shift assay proved that TOE3 activated the transcription of KL1 and MLP43 by binding their promoters. Moreover, overexpression of rTOE3 (the miR172‐resistant form of TOE3) significantly reduced TMV accumulation compared to the overexpression of TOE3 (the normal form of TOE3) in miR172 overexpressing Nicotiana benthamiana plants. Taken together, our study reveals the pivotal role of miR172/TOE3 module in regulating plant immunity and in the establishment of recovery in virus‐infected tobacco plants, elucidating a regulatory mechanism integrating plant growth, development, and immune response.
Significance Statement
miR172/TOE3 module is well‐known for its role in regulating reproductive process. In this study, we demonstrated that miR172/TOE3 module plays an important role in regulating the resistance of tobacco to TMV infection and the formation of symptom recovery.</description><subject>Bioaccumulation</subject><subject>Canonical forms</subject><subject>Chromatin</subject><subject>defense‐related gene</subject><subject>Disease control</subject><subject>Disease resistance</subject><subject>Disease Resistance - genetics</subject><subject>Electrophoretic mobility</subject><subject>gel electrophoresis</subject><subject>Gene Expression Regulation, Plant</subject><subject>Genes</subject><subject>Immune response</subject><subject>Immune system</subject><subject>Immunoprecipitation</subject><subject>Infections</subject><subject>microRNA</subject><subject>MicroRNAs</subject><subject>MicroRNAs - genetics</subject><subject>MicroRNAs - metabolism</subject><subject>miR172/TOE3</subject><subject>miRNA</subject><subject>Modules</subject><subject>Nicotiana - genetics</subject><subject>Nicotiana - immunology</subject><subject>Nicotiana - virology</subject><subject>Nicotiana benthamiana</subject><subject>Nicotiana tabacum</subject><subject>Plant Diseases - genetics</subject><subject>Plant Diseases - immunology</subject><subject>Plant Diseases - virology</subject><subject>Plant growth</subject><subject>Plant immunity</subject><subject>Plant layout</subject><subject>Plant Proteins - genetics</subject><subject>Plant Proteins - metabolism</subject><subject>Plant resistance</subject><subject>Plant virus diseases</subject><subject>Plant viruses</subject><subject>Plants, Genetically Modified</subject><subject>Recovery</subject><subject>Regulatory mechanisms (biology)</subject><subject>symptom recovery</subject><subject>Tobacco</subject><subject>Tobacco mosaic virus</subject><subject>Tobacco Mosaic Virus - physiology</subject><subject>Tobamovirus</subject><subject>transcription factors</subject><subject>Transcription Factors - genetics</subject><subject>Transcription Factors - metabolism</subject><subject>Transcriptomes</subject><subject>transcriptomics</subject><subject>Viral diseases</subject><subject>Viruses</subject><issn>0960-7412</issn><issn>1365-313X</issn><issn>1365-313X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0U1LwzAYB_AgipvTg19ACl70UJcnr-1RxnxjOJEK3kqbJtrRrjNplX17o908CGIIJIQf_4fwR-gY8AX4NW5XiwsQMYMdNAQqeEiBPu-iIY4FDiUDMkAHzi0wBkkF20cDGmOGMeZDdJ-86qAuH0GScTKf0qBuiq7SgdUvXZW12vmbK12bLZUO2sbvPFOq8cxlpQreS9u5oFxu3w_Rnskqp4825wg9XU2TyU04m1_fTi5noSJSQKiMEEoUPFIUDKZUC0K4ig0wKSLFDSOSSYUpzw2JaG7yqBBaR9hgk3Ewio7QWZ-7ss1bp12b1qVTuqqypW46l1LgDCImJfuf4ogKGfuBnp7-ooums0v_ER9IIhCcyNir814p2zhntUlXtqwzu04Bp199pL6P9LsPb082iV1e6-JHbgvwYNyDj7LS67-T0uThro_8BNLMkfk</recordid><startdate>202409</startdate><enddate>202409</enddate><creator>Jiao, Bolei</creator><creator>Peng, Qiding</creator><creator>Wu, Baijun</creator><creator>Liu, Sucen</creator><creator>Zhou, Jingya</creator><creator>Yuan, Bowen</creator><creator>Lin, Honghui</creator><creator>Xi, Dehui</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7QP</scope><scope>7QR</scope><scope>7TM</scope><scope>8FD</scope><scope>FR3</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>7S9</scope><scope>L.6</scope><orcidid>https://orcid.org/0000-0002-1314-1262</orcidid></search><sort><creationdate>202409</creationdate><title>The miR172/TOE3 module regulates resistance to tobacco mosaic virus in tobacco</title><author>Jiao, Bolei ; Peng, Qiding ; Wu, Baijun ; Liu, Sucen ; Zhou, Jingya ; Yuan, Bowen ; Lin, Honghui ; Xi, Dehui</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2761-cf66c6d58c31f033e6225c9f14768c5f42747c035bf283bfb8d6ee80f0fa51fc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Bioaccumulation</topic><topic>Canonical forms</topic><topic>Chromatin</topic><topic>defense‐related gene</topic><topic>Disease control</topic><topic>Disease resistance</topic><topic>Disease Resistance - genetics</topic><topic>Electrophoretic mobility</topic><topic>gel electrophoresis</topic><topic>Gene Expression Regulation, Plant</topic><topic>Genes</topic><topic>Immune response</topic><topic>Immune system</topic><topic>Immunoprecipitation</topic><topic>Infections</topic><topic>microRNA</topic><topic>MicroRNAs</topic><topic>MicroRNAs - genetics</topic><topic>MicroRNAs - metabolism</topic><topic>miR172/TOE3</topic><topic>miRNA</topic><topic>Modules</topic><topic>Nicotiana - genetics</topic><topic>Nicotiana - immunology</topic><topic>Nicotiana - virology</topic><topic>Nicotiana benthamiana</topic><topic>Nicotiana tabacum</topic><topic>Plant Diseases - genetics</topic><topic>Plant Diseases - immunology</topic><topic>Plant Diseases - virology</topic><topic>Plant growth</topic><topic>Plant immunity</topic><topic>Plant layout</topic><topic>Plant Proteins - genetics</topic><topic>Plant Proteins - metabolism</topic><topic>Plant resistance</topic><topic>Plant virus diseases</topic><topic>Plant viruses</topic><topic>Plants, Genetically Modified</topic><topic>Recovery</topic><topic>Regulatory mechanisms (biology)</topic><topic>symptom recovery</topic><topic>Tobacco</topic><topic>Tobacco mosaic virus</topic><topic>Tobacco Mosaic Virus - physiology</topic><topic>Tobamovirus</topic><topic>transcription factors</topic><topic>Transcription Factors - genetics</topic><topic>Transcription Factors - metabolism</topic><topic>Transcriptomes</topic><topic>transcriptomics</topic><topic>Viral diseases</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jiao, Bolei</creatorcontrib><creatorcontrib>Peng, Qiding</creatorcontrib><creatorcontrib>Wu, Baijun</creatorcontrib><creatorcontrib>Liu, Sucen</creatorcontrib><creatorcontrib>Zhou, Jingya</creatorcontrib><creatorcontrib>Yuan, Bowen</creatorcontrib><creatorcontrib>Lin, Honghui</creatorcontrib><creatorcontrib>Xi, Dehui</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><jtitle>The Plant journal : for cell and molecular biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jiao, Bolei</au><au>Peng, Qiding</au><au>Wu, Baijun</au><au>Liu, Sucen</au><au>Zhou, Jingya</au><au>Yuan, Bowen</au><au>Lin, Honghui</au><au>Xi, Dehui</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The miR172/TOE3 module regulates resistance to tobacco mosaic virus in tobacco</atitle><jtitle>The Plant journal : for cell and molecular biology</jtitle><addtitle>Plant J</addtitle><date>2024-09</date><risdate>2024</risdate><volume>119</volume><issue>6</issue><spage>2672</spage><epage>2686</epage><pages>2672-2686</pages><issn>0960-7412</issn><issn>1365-313X</issn><eissn>1365-313X</eissn><abstract>SUMMARY
The outcome of certain plant–virus interaction is symptom recovery, which is accompanied with the emergence of asymptomatic tissues in which the virus accumulation decreased dramatically. This phenomenon shows the potential to reveal critical molecular factors for controlling viral disease. MicroRNAs act as master regulators in plant growth, development, and immunity. However, the mechanism by which miRNA participates in regulating symptom recovery remains largely unknown. Here, we reported that miR172 was scavenged in the recovered tissue of tobacco mosaic virus (TMV)‐infected Nicotiana tabacum plants. Overexpression of miR172 promoted TMV infection, whereas silencing of miR172 inhibited TMV infection. Then, TARGET OF EAT3 (TOE3), an APETALA2 transcription factor, was identified as a downstream target of miR172. Overexpression of NtTOE3 significantly improved plant resistance to TMV infection, while knockout of NtTOE3 facilitated virus infection. Furthermore, transcriptome analysis indicated that TOE3 promoted the expression of defense‐related genes, such as KL1 and MLP43. Overexpression of these genes conferred resistance of plant against TMV infection. Importantly, results of dual‐luciferase assay, chromatin immunoprecipitation‐quantitative PCR, and electrophoretic mobility shift assay proved that TOE3 activated the transcription of KL1 and MLP43 by binding their promoters. Moreover, overexpression of rTOE3 (the miR172‐resistant form of TOE3) significantly reduced TMV accumulation compared to the overexpression of TOE3 (the normal form of TOE3) in miR172 overexpressing Nicotiana benthamiana plants. Taken together, our study reveals the pivotal role of miR172/TOE3 module in regulating plant immunity and in the establishment of recovery in virus‐infected tobacco plants, elucidating a regulatory mechanism integrating plant growth, development, and immune response.
Significance Statement
miR172/TOE3 module is well‐known for its role in regulating reproductive process. In this study, we demonstrated that miR172/TOE3 module plays an important role in regulating the resistance of tobacco to TMV infection and the formation of symptom recovery.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>39040005</pmid><doi>10.1111/tpj.16941</doi><tpages>15</tpages><orcidid>https://orcid.org/0000-0002-1314-1262</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0960-7412 |
| ispartof | The Plant journal : for cell and molecular biology, 2024-09, Vol.119 (6), p.2672-2686 |
| issn | 0960-7412 1365-313X 1365-313X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_3083679747 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Bioaccumulation Canonical forms Chromatin defense‐related gene Disease control Disease resistance Disease Resistance - genetics Electrophoretic mobility gel electrophoresis Gene Expression Regulation, Plant Genes Immune response Immune system Immunoprecipitation Infections microRNA MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miR172/TOE3 miRNA Modules Nicotiana - genetics Nicotiana - immunology Nicotiana - virology Nicotiana benthamiana Nicotiana tabacum Plant Diseases - genetics Plant Diseases - immunology Plant Diseases - virology Plant growth Plant immunity Plant layout Plant Proteins - genetics Plant Proteins - metabolism Plant resistance Plant virus diseases Plant viruses Plants, Genetically Modified Recovery Regulatory mechanisms (biology) symptom recovery Tobacco Tobacco mosaic virus Tobacco Mosaic Virus - physiology Tobamovirus transcription factors Transcription Factors - genetics Transcription Factors - metabolism Transcriptomes transcriptomics Viral diseases Viruses |
| title | The miR172/TOE3 module regulates resistance to tobacco mosaic virus in tobacco |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T16%3A13%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20miR172/TOE3%20module%20regulates%20resistance%20to%20tobacco%20mosaic%20virus%20in%20tobacco&rft.jtitle=The%20Plant%20journal%20:%20for%20cell%20and%20molecular%20biology&rft.au=Jiao,%20Bolei&rft.date=2024-09&rft.volume=119&rft.issue=6&rft.spage=2672&rft.epage=2686&rft.pages=2672-2686&rft.issn=0960-7412&rft.eissn=1365-313X&rft_id=info:doi/10.1111/tpj.16941&rft_dat=%3Cproquest_cross%3E3154184774%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3128165279&rft_id=info:pmid/39040005&rfr_iscdi=true |