Structural analysis of peptide identified from the 2KRR domain of the nucleolin protein with a c-Myc G4 structure using biophysical and biochemical methods

For the first time, the c-Myc G4 structure is reported to be stabilized by binding of the peptide (derived from the 2KRR domain of the nucleolin protein called the Nu peptide) in the loop region of the G-quadruplex structure by stacking interactions. CD results showed the formation of parallel G4 st...

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Veröffentlicht in:	RSC advances 2024-07, Vol.14 (32), p.22801-22808
Hauptverfasser:	Kaur, Sarvpreet, Kundu, Nikita, Sharma, Taniya, Shankaraswamy, J, Singh, Sweta, Saxena, Sarika
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Peptides Proteins Structural analysis
Online-Zugang:	Volltext
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