Exploring the role of mesenchymal stem cells in modulating immune responses via Treg and Th2 cell activation: insights from mouse model of multiple sclerosis

Multiple sclerosis is a demyelinating neurodegenerative disease, and its animal model, experimental autoimmune encephalomyelitis (EAE), exhibits immunological and clinical similarities. The study aimed to examine mechanisms underlying therapeutic effects of mesenchymal stem cell administration in EA...

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Veröffentlicht in:	APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2024-11, Vol.132 (11), p.888-899
Hauptverfasser:	Sadeghnejad, Abdolvahid, Pazoki, Alireza, Yazdanpanah, Esmaeil, Esmaeili, Seyed‐Alireza, Yousefi, Bahman, Sadighi‐Moghaddam, Bijan, Baharlou, Rasoul, Haghmorad, Dariush
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal diseases Animal models Animals Autoimmune diseases bone marrow mesenchymal stem cells Cell activation Cell proliferation Cytokines Demyelination Experimental allergic encephalomyelitis experimental autoimmune encephalomyelitis Gene expression Health services Helper cells Immune response Immunology Lymphocytes Lymphocytes T Medical treatment Mesenchymal stem cells Multiple sclerosis Neurodegenerative diseases Signs and symptoms Spinal cord Spleen Stem cells
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