HO-1 activation contributes to cadmium-induced ferroptosis in renal tubular epithelial cells via increasing the labile iron pool and promoting mitochondrial ROS generation

Cadmium (Cd), a prevalent environmental contaminant, has attracted widespread attention due to its serious health hazards. Ferroptosis is a form of iron-dependent oxidative cell death that contributes to the development of various kidney diseases. However, the mechanisms underlying the occurrence of...

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Veröffentlicht in:	Chemico-biological interactions 2024-08, Vol.399, p.111152, Article 111152
Hauptverfasser:	Lv, Yan-Ting, Liu, Tian-Bin, Li, Yue, Wang, Zhen-Yong, Lian, Cai-Yu, Wang, Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Cadmium Ferroptosis HO-1 Lipid peroxidation Renal tubule epithelial cell
Online-Zugang:	Volltext
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