Blood levels of metallic chemical element exposure patterns and associated factors in a population living in an Industrial District in Brazil
AIM:to estimate the level of metallic chemical elements in the population living in the Steel company vicinity in Santa Cruz, Rio de Janeiro, Brazil; and estimate the association between exposure to the Steel company and the blood metals concentrations patterns.METHOD:A cross-sectional study was car...
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| Veröffentlicht in: | Journal of trace elements in medicine and biology 2024-09, Vol.85, p.127498, Article 127498 |
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| creator | Lemos, Maria Cristina Ferreira Koifman, Rosalina Jorge Barbosa Jr, Fernando Saraceni, Valéria Quadros, Evanelza Pinheiro, Rafael do Nascimento Souza, Vanessa Cristina de Oliveira Costa, Rafaela Soares Senra da Silva, Ilce Ferreira da |
| description | AIM:to estimate the level of metallic chemical elements in the population living in the Steel company vicinity in Santa Cruz, Rio de Janeiro, Brazil; and estimate the association between exposure to the Steel company and the blood metals concentrations patterns.METHOD:A cross-sectional study was carried out on 463 individuals aged 18+ years old residing 1+ years in the Steel company vicinity. Mg, Be, Co, Ba, Ni, Cd, Al, and Pb were assessed in blood by DRC-ICP-MS. Metallic chemical element concentration patterns were obtained by exploratory factor analysis in the studied population. Exposure was set as the distance (Km) from each participant's residence to the Steel company in Santa Cruz, georeferenced by GPS. The outcome was set as the positive factor loadings in the factor analysis, including Mg and Be (Factor-1), Co, Ba, and Ni (Factor-2), Cd, Al, and Pb (Factor-4). Crude and adjusted OR, and their respective 95 %CI, were estimated to explore associations between independent variables and the exposures to metallic elements positively associated with the factors using polychotomous logistic regression.RESULTS:A reduction of 19 % was found between each km distance from the residence and the Steel company and P50 concentration of Cd, Al, and Pb (ORP50=0.81; 95 %CI:0.67–0.97), after adjusting by age, sex, and smoking. No statistically significant associations were observed for the distance from residences and the Steel company, after adjusting for age, gender, having a domestic vegetable garden and chewing gum for Mg and Be concentrations (Factor-1) (ORP50=0.84; 95 %CI:0.70–1.01; ORP75=1.10; 95 %CI:0.91–1.34); nor for Co, Ba and Ni (Factor-2) blood concentrations(ORP50=1.10; 95 %CI:0.91–1.33; ORP75=1.03; 95 %CI:0.84–1.26), in the adjusted analysis.CONCLUSIONS: For each Km distance from residences to the Steel company, a 19 % reduction in the risk of Cd, Al, and Pb blood concentration was observed in the population living in Santa Cruz, Rio de Janeiro, Brazil.
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| doi_str_mv | 10.1016/j.jtemb.2024.127498 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3082627311</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0946672X24001184</els_id><sourcerecordid>3082627311</sourcerecordid><originalsourceid>FETCH-LOGICAL-c239t-5b991390aa014b0425eb56d503e296eb6446d98f9ce0b50dd2283944c2e8a1793</originalsourceid><addsrcrecordid>eNp9UU1v1DAQtRAV3RZ-ARLykUsWfyWxDxxogVKpUi8gcbMcewJeOXawnRXtf-A_k-2WHjnNaOa9eZr3EHpNyZYS2r3bbXcVpmHLCBNbynqh5DO0obKXDWcte442RImu6Xr2_RSdlbIjhPatZC_QKVcrR7Zkg_5chJQcDrCHUHAa8QTVhOAttj9h8tYEDAEmiBXD7zmVJQOeTa2QY8EmOmxKSdabCg6PxtaUC_YRGzyneQmm-hRx8HsffzyMI76Obik1-_XwR39obD1sLrK59-ElOhlNKPDqsZ6jb58_fb380tzcXl1ffrhpLOOqNu2gFF1_MIZQMRDBWhjazrWEA1MdDJ0QnVNyVBbI0BLnGJNcCWEZSEN7xc_R2-PdOadfC5SqJ18shGAipKVoTiTrWM8pXaH8CLU5lZJh1HP2k8l3mhJ9yEHv9EMO-pCDPuawst48CizDBO6J88_4FfD-CFhth72HrIv1EC04n8FW7ZL_r8Bfj1ycMQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3082627311</pqid></control><display><type>article</type><title>Blood levels of metallic chemical element exposure patterns and associated factors in a population living in an Industrial District in Brazil</title><source>ScienceDirect Journals (5 years ago - present)</source><creator>Lemos, Maria Cristina Ferreira ; Koifman, Rosalina Jorge ; Barbosa Jr, Fernando ; Saraceni, Valéria ; Quadros, Evanelza ; Pinheiro, Rafael do Nascimento ; Souza, Vanessa Cristina de Oliveira ; Costa, Rafaela Soares Senra da ; Silva, Ilce Ferreira da</creator><creatorcontrib>Lemos, Maria Cristina Ferreira ; Koifman, Rosalina Jorge ; Barbosa Jr, Fernando ; Saraceni, Valéria ; Quadros, Evanelza ; Pinheiro, Rafael do Nascimento ; Souza, Vanessa Cristina de Oliveira ; Costa, Rafaela Soares Senra da ; Silva, Ilce Ferreira da</creatorcontrib><description>AIM:to estimate the level of metallic chemical elements in the population living in the Steel company vicinity in Santa Cruz, Rio de Janeiro, Brazil; and estimate the association between exposure to the Steel company and the blood metals concentrations patterns.METHOD:A cross-sectional study was carried out on 463 individuals aged 18+ years old residing 1+ years in the Steel company vicinity. Mg, Be, Co, Ba, Ni, Cd, Al, and Pb were assessed in blood by DRC-ICP-MS. Metallic chemical element concentration patterns were obtained by exploratory factor analysis in the studied population. Exposure was set as the distance (Km) from each participant's residence to the Steel company in Santa Cruz, georeferenced by GPS. The outcome was set as the positive factor loadings in the factor analysis, including Mg and Be (Factor-1), Co, Ba, and Ni (Factor-2), Cd, Al, and Pb (Factor-4). Crude and adjusted OR, and their respective 95 %CI, were estimated to explore associations between independent variables and the exposures to metallic elements positively associated with the factors using polychotomous logistic regression.RESULTS:A reduction of 19 % was found between each km distance from the residence and the Steel company and P50 concentration of Cd, Al, and Pb (ORP50=0.81; 95 %CI:0.67–0.97), after adjusting by age, sex, and smoking. No statistically significant associations were observed for the distance from residences and the Steel company, after adjusting for age, gender, having a domestic vegetable garden and chewing gum for Mg and Be concentrations (Factor-1) (ORP50=0.84; 95 %CI:0.70–1.01; ORP75=1.10; 95 %CI:0.91–1.34); nor for Co, Ba and Ni (Factor-2) blood concentrations(ORP50=1.10; 95 %CI:0.91–1.33; ORP75=1.03; 95 %CI:0.84–1.26), in the adjusted analysis.CONCLUSIONS: For each Km distance from residences to the Steel company, a 19 % reduction in the risk of Cd, Al, and Pb blood concentration was observed in the population living in Santa Cruz, Rio de Janeiro, Brazil.
[Display omitted]</description><identifier>ISSN: 0946-672X</identifier><identifier>ISSN: 1878-3252</identifier><identifier>EISSN: 1878-3252</identifier><identifier>DOI: 10.1016/j.jtemb.2024.127498</identifier><identifier>PMID: 39024850</identifier><language>eng</language><publisher>Germany: Elsevier GmbH</publisher><subject>Environmental exposure ; Factor analysis ; Human Biomonitoring ; Industrial exposures ; Metallic chemical elements</subject><ispartof>Journal of trace elements in medicine and biology, 2024-09, Vol.85, p.127498, Article 127498</ispartof><rights>2024 Elsevier GmbH</rights><rights>Copyright © 2024 Elsevier GmbH. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c239t-5b991390aa014b0425eb56d503e296eb6446d98f9ce0b50dd2283944c2e8a1793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jtemb.2024.127498$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27923,27924,45994</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39024850$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lemos, Maria Cristina Ferreira</creatorcontrib><creatorcontrib>Koifman, Rosalina Jorge</creatorcontrib><creatorcontrib>Barbosa Jr, Fernando</creatorcontrib><creatorcontrib>Saraceni, Valéria</creatorcontrib><creatorcontrib>Quadros, Evanelza</creatorcontrib><creatorcontrib>Pinheiro, Rafael do Nascimento</creatorcontrib><creatorcontrib>Souza, Vanessa Cristina de Oliveira</creatorcontrib><creatorcontrib>Costa, Rafaela Soares Senra da</creatorcontrib><creatorcontrib>Silva, Ilce Ferreira da</creatorcontrib><title>Blood levels of metallic chemical element exposure patterns and associated factors in a population living in an Industrial District in Brazil</title><title>Journal of trace elements in medicine and biology</title><addtitle>J Trace Elem Med Biol</addtitle><description>AIM:to estimate the level of metallic chemical elements in the population living in the Steel company vicinity in Santa Cruz, Rio de Janeiro, Brazil; and estimate the association between exposure to the Steel company and the blood metals concentrations patterns.METHOD:A cross-sectional study was carried out on 463 individuals aged 18+ years old residing 1+ years in the Steel company vicinity. Mg, Be, Co, Ba, Ni, Cd, Al, and Pb were assessed in blood by DRC-ICP-MS. Metallic chemical element concentration patterns were obtained by exploratory factor analysis in the studied population. Exposure was set as the distance (Km) from each participant's residence to the Steel company in Santa Cruz, georeferenced by GPS. The outcome was set as the positive factor loadings in the factor analysis, including Mg and Be (Factor-1), Co, Ba, and Ni (Factor-2), Cd, Al, and Pb (Factor-4). Crude and adjusted OR, and their respective 95 %CI, were estimated to explore associations between independent variables and the exposures to metallic elements positively associated with the factors using polychotomous logistic regression.RESULTS:A reduction of 19 % was found between each km distance from the residence and the Steel company and P50 concentration of Cd, Al, and Pb (ORP50=0.81; 95 %CI:0.67–0.97), after adjusting by age, sex, and smoking. No statistically significant associations were observed for the distance from residences and the Steel company, after adjusting for age, gender, having a domestic vegetable garden and chewing gum for Mg and Be concentrations (Factor-1) (ORP50=0.84; 95 %CI:0.70–1.01; ORP75=1.10; 95 %CI:0.91–1.34); nor for Co, Ba and Ni (Factor-2) blood concentrations(ORP50=1.10; 95 %CI:0.91–1.33; ORP75=1.03; 95 %CI:0.84–1.26), in the adjusted analysis.CONCLUSIONS: For each Km distance from residences to the Steel company, a 19 % reduction in the risk of Cd, Al, and Pb blood concentration was observed in the population living in Santa Cruz, Rio de Janeiro, Brazil.
[Display omitted]</description><subject>Environmental exposure</subject><subject>Factor analysis</subject><subject>Human Biomonitoring</subject><subject>Industrial exposures</subject><subject>Metallic chemical elements</subject><issn>0946-672X</issn><issn>1878-3252</issn><issn>1878-3252</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9UU1v1DAQtRAV3RZ-ARLykUsWfyWxDxxogVKpUi8gcbMcewJeOXawnRXtf-A_k-2WHjnNaOa9eZr3EHpNyZYS2r3bbXcVpmHLCBNbynqh5DO0obKXDWcte442RImu6Xr2_RSdlbIjhPatZC_QKVcrR7Zkg_5chJQcDrCHUHAa8QTVhOAttj9h8tYEDAEmiBXD7zmVJQOeTa2QY8EmOmxKSdabCg6PxtaUC_YRGzyneQmm-hRx8HsffzyMI76Obik1-_XwR39obD1sLrK59-ElOhlNKPDqsZ6jb58_fb380tzcXl1ffrhpLOOqNu2gFF1_MIZQMRDBWhjazrWEA1MdDJ0QnVNyVBbI0BLnGJNcCWEZSEN7xc_R2-PdOadfC5SqJ18shGAipKVoTiTrWM8pXaH8CLU5lZJh1HP2k8l3mhJ9yEHv9EMO-pCDPuawst48CizDBO6J88_4FfD-CFhth72HrIv1EC04n8FW7ZL_r8Bfj1ycMQ</recordid><startdate>20240901</startdate><enddate>20240901</enddate><creator>Lemos, Maria Cristina Ferreira</creator><creator>Koifman, Rosalina Jorge</creator><creator>Barbosa Jr, Fernando</creator><creator>Saraceni, Valéria</creator><creator>Quadros, Evanelza</creator><creator>Pinheiro, Rafael do Nascimento</creator><creator>Souza, Vanessa Cristina de Oliveira</creator><creator>Costa, Rafaela Soares Senra da</creator><creator>Silva, Ilce Ferreira da</creator><general>Elsevier GmbH</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20240901</creationdate><title>Blood levels of metallic chemical element exposure patterns and associated factors in a population living in an Industrial District in Brazil</title><author>Lemos, Maria Cristina Ferreira ; Koifman, Rosalina Jorge ; Barbosa Jr, Fernando ; Saraceni, Valéria ; Quadros, Evanelza ; Pinheiro, Rafael do Nascimento ; Souza, Vanessa Cristina de Oliveira ; Costa, Rafaela Soares Senra da ; Silva, Ilce Ferreira da</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c239t-5b991390aa014b0425eb56d503e296eb6446d98f9ce0b50dd2283944c2e8a1793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Environmental exposure</topic><topic>Factor analysis</topic><topic>Human Biomonitoring</topic><topic>Industrial exposures</topic><topic>Metallic chemical elements</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lemos, Maria Cristina Ferreira</creatorcontrib><creatorcontrib>Koifman, Rosalina Jorge</creatorcontrib><creatorcontrib>Barbosa Jr, Fernando</creatorcontrib><creatorcontrib>Saraceni, Valéria</creatorcontrib><creatorcontrib>Quadros, Evanelza</creatorcontrib><creatorcontrib>Pinheiro, Rafael do Nascimento</creatorcontrib><creatorcontrib>Souza, Vanessa Cristina de Oliveira</creatorcontrib><creatorcontrib>Costa, Rafaela Soares Senra da</creatorcontrib><creatorcontrib>Silva, Ilce Ferreira da</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of trace elements in medicine and biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lemos, Maria Cristina Ferreira</au><au>Koifman, Rosalina Jorge</au><au>Barbosa Jr, Fernando</au><au>Saraceni, Valéria</au><au>Quadros, Evanelza</au><au>Pinheiro, Rafael do Nascimento</au><au>Souza, Vanessa Cristina de Oliveira</au><au>Costa, Rafaela Soares Senra da</au><au>Silva, Ilce Ferreira da</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Blood levels of metallic chemical element exposure patterns and associated factors in a population living in an Industrial District in Brazil</atitle><jtitle>Journal of trace elements in medicine and biology</jtitle><addtitle>J Trace Elem Med Biol</addtitle><date>2024-09-01</date><risdate>2024</risdate><volume>85</volume><spage>127498</spage><pages>127498-</pages><artnum>127498</artnum><issn>0946-672X</issn><issn>1878-3252</issn><eissn>1878-3252</eissn><abstract>AIM:to estimate the level of metallic chemical elements in the population living in the Steel company vicinity in Santa Cruz, Rio de Janeiro, Brazil; and estimate the association between exposure to the Steel company and the blood metals concentrations patterns.METHOD:A cross-sectional study was carried out on 463 individuals aged 18+ years old residing 1+ years in the Steel company vicinity. Mg, Be, Co, Ba, Ni, Cd, Al, and Pb were assessed in blood by DRC-ICP-MS. Metallic chemical element concentration patterns were obtained by exploratory factor analysis in the studied population. Exposure was set as the distance (Km) from each participant's residence to the Steel company in Santa Cruz, georeferenced by GPS. The outcome was set as the positive factor loadings in the factor analysis, including Mg and Be (Factor-1), Co, Ba, and Ni (Factor-2), Cd, Al, and Pb (Factor-4). Crude and adjusted OR, and their respective 95 %CI, were estimated to explore associations between independent variables and the exposures to metallic elements positively associated with the factors using polychotomous logistic regression.RESULTS:A reduction of 19 % was found between each km distance from the residence and the Steel company and P50 concentration of Cd, Al, and Pb (ORP50=0.81; 95 %CI:0.67–0.97), after adjusting by age, sex, and smoking. No statistically significant associations were observed for the distance from residences and the Steel company, after adjusting for age, gender, having a domestic vegetable garden and chewing gum for Mg and Be concentrations (Factor-1) (ORP50=0.84; 95 %CI:0.70–1.01; ORP75=1.10; 95 %CI:0.91–1.34); nor for Co, Ba and Ni (Factor-2) blood concentrations(ORP50=1.10; 95 %CI:0.91–1.33; ORP75=1.03; 95 %CI:0.84–1.26), in the adjusted analysis.CONCLUSIONS: For each Km distance from residences to the Steel company, a 19 % reduction in the risk of Cd, Al, and Pb blood concentration was observed in the population living in Santa Cruz, Rio de Janeiro, Brazil.
[Display omitted]</abstract><cop>Germany</cop><pub>Elsevier GmbH</pub><pmid>39024850</pmid><doi>10.1016/j.jtemb.2024.127498</doi></addata></record> |
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| ispartof | Journal of trace elements in medicine and biology, 2024-09, Vol.85, p.127498, Article 127498 |
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| language | eng |
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| source | ScienceDirect Journals (5 years ago - present) |
| subjects | Environmental exposure Factor analysis Human Biomonitoring Industrial exposures Metallic chemical elements |
| title | Blood levels of metallic chemical element exposure patterns and associated factors in a population living in an Industrial District in Brazil |
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