Ticagrelor 60 vs. 90 mg in elderly ACS patients undergoing PCI: a randomized, crossover trial

Although dual antiplatelet therapy with aspirin and a potent P2Y12 receptor inhibitor is currently recommended in patients with acute coronary syndrome (ACS), its use in elderly patients remains challenging. The aim of this trial is to evaluate the pharmacodynamic and pharmacokinetic profile of tica...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European heart journal. Cardiovascular pharmacotherapy 2024-11, Vol.10 (7), p.578-587
Hauptverfasser:	Piccolo, Raffaele, Simonetti, Fiorenzo, Avvedimento, Marisa, Cutillo, Maria, Canonico, Mario Enrico, Conti, Valeria, Gargiulo, Giuseppe, Paolillo, Roberta, Dal Piaz, Fabrizio, Filippelli, Amelia, Charlier, Bruno, Spinelli, Alessandra, Cristiano, Stefano, Cirillo, Plinio, Di Serafino, Luigi, Franzone, Anna, Esposito, Giovanni
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Coronary Syndrome - blood Acute Coronary Syndrome - diagnosis Acute Coronary Syndrome - drug therapy Acute Coronary Syndrome - therapy Age Factors Aged Aged patients Aged, 80 and over Aggregation Aspirin - administration & dosage Aspirin - adverse effects Aspirin - pharmacokinetics Blood platelets Blood Platelets - drug effects Blood Platelets - metabolism Cardiac patients Care and treatment Coronary heart disease Cross-Over Studies Drug Administration Schedule Female Humans Male Metabolites Percutaneous Coronary Intervention - adverse effects Platelet Aggregation - drug effects Platelet Aggregation Inhibitors - administration & dosage Platelet Aggregation Inhibitors - adverse effects Platelet Aggregation Inhibitors - pharmacokinetics Platelet Function Tests Purinergic P2Y Receptor Antagonists - administration & dosage Purinergic P2Y Receptor Antagonists - adverse effects Purinergic P2Y Receptor Antagonists - pharmacokinetics Receptors, Purinergic P2Y12 - blood Receptors, Purinergic P2Y12 - drug effects Ticagrelor - administration & dosage Ticagrelor - adverse effects Ticagrelor - pharmacokinetics Time Factors Transluminal angioplasty Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!