How Membrane Phospholipids Containing Long-Chain Polyunsaturated Fatty Acids and Their Oxidation Products Orchestrate Lipid Raft Dynamics to Control Inflammation

Long-chain PUFA (LC-PUFA) influence varying aspects of inflammation. One mechanism by which they regulate inflammation is by controlling the size and molecular composition of lipid rafts. Lipid rafts are sphingolipid/cholesterol-enriched plasma membrane microdomains that compartmentalize signaling p...

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Veröffentlicht in:	The Journal of nutrition 2024-09, Vol.154 (9), p.2862-2870
Hauptverfasser:	Virk, Rafia, Cook, Katie, Cavazos, Andres, Wassall, Stephen R, Gowdy, Kymberly M, Shaikh, Saame Raza
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive control Adaptive immunity Biomimetics Cell surface receptors Chemical composition Cholesterol Docosahexaenoic acid Eicosapentaenoic acid Fatty acids Gene expression Homeostasis immune cells Inflammation Lecithin Lipid rafts Lipids Lymphoid cells Membranes Molecular chains Molecular dynamics Molecular modelling Oxidation oxidized phospholipids Phosphatidylcholine Phospholipids plasma membrane Polyunsaturated fatty acids Proteins Rafts
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