Mucosal signatures of pathogenic T cells in HLA-B27+ anterior uveitis and axial spondyloarthritis

HLA-B*27 was one of the first HLA alleles associated with an autoimmune disease, i.e., axial spondyloarthritis (axSpA) and acute anterior uveitis (B27AAU), which cause joint and eye inflammation, respectively. Gastrointestinal inflammation has been suggested as a trigger of axSpA. We recently identi...

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Veröffentlicht in:JCI insight 2024-07, Vol.9 (16)
Hauptverfasser: Paley, Michael A, Yang, Xinbo, Hassman, Lynn M, Penkava, Frank, Garner, Lee I, Paley, Grace L, Linskey, Nicole, Agnew, Ryan, Arantes de Faria, Paulo Henrique, Feng, Annie, Li, Sophia Y, Simone, Davide, Roberson, Elisha DO, Ruzycki, Philip A, Esaulova, Ekaterina, Laurent, Jennifer, Feigl-Lenzen, Lacey, Springer, Luke E, Liu, Chang, Gillespie, Geraldine M, Bowness, Paul, Garcia, K Christopher, Yokoyama, Wayne M
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Sprache:eng
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