Metabolic syndrome induces benefits in mice experiencing severe sepsis, comparable to the effects of low-dose aspirin pretreatment in septic mice lacking metabolic syndrome

[Display omitted] •Metabolic Syndrome (MetS) protected from severe sepsis increasing survival rates.•Aspirin (ASA) pre-treatment was effective in improving survival in lean animals.•ASA pre-treatment was not effective to MetS septic animals.•Survival in ASA-treated control mice was similar to MetS-p...

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Veröffentlicht in:International immunopharmacology 2024-09, Vol.139, p.112694, Article 112694
Hauptverfasser: Nakama, Raquel Pires, dos Santos, Lucas Felipe, Berto-Pereira, Leonardo, de Rossi, Lucas Sobral, Malvezi, Aparecida Donizette, Lovo-Martins, Maria Isabel, Canizares Cardoso, Ana Paula, de Freitas, Andressa Mendes Dionísio, Martins-Pinge, Marli Cardoso, Pinge-Filho, Phileno
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Sprache:eng
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