Preoperative short‐course radiotherapy followed by chemotherapy and PD‐1 inhibitor administration for locally advanced rectal cancer: A study protocol of a randomized phase II/III trial (STELLAR II study)

Aim For patients with locally advanced rectal cancer, previous STELLAR studies have shown that a new adjuvant treatment paradigm of short‐course radiotherapy followed by neoadjuvant chemotherapy can achieve pathological complete response rates superior to those of standard care; however, the 3‐year...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Colorectal disease 2024-09, Vol.26 (9), p.1732-1740
Hauptverfasser:	Zhang, Wenjue, Tang, Yuan, Wei, Lichun, Liu, Shixin, Wang, Wenling, Chi, Yihebali, Wang, Ying, Kang, Wenyan, Huang, Wenting, Deng, Feiyan, Li, Haoyue, Ma, Huiying, Jiang, LiMing, Ding, Zhen, Feng, Lingling, Li, Yexiong, Chen, Yinggang, Zhou, Haitao, Hu, Chen, Jin, Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Cancer Chemotherapy Clinical Trials, Phase II as Topic Clinical Trials, Phase III as Topic Colorectal cancer Disease management Female Humans Immune checkpoint inhibitors Immune Checkpoint Inhibitors - administration & dosage Immune Checkpoint Inhibitors - therapeutic use Immunotherapy locally advanced rectal cancer Male Medical prognosis Metastases Middle Aged Multicenter Studies as Topic Neoadjuvant Therapy - methods Prognosis Quality of life Radiation therapy Randomized Controlled Trials as Topic Rectal Neoplasms - pathology Rectal Neoplasms - therapy Rectum Remission Response rates short‐course radiotherapy total neoadjuvant therapy Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!