Site-Specific Glycosylation Analysis of Human and Murine Fcγ Receptor II Family Members Reveals Variant-Specific N‑Glycosylation

Fcγ-receptors (FcγRs) including FcγRII (CD32) gene family members are expressed on leukocytes, bind the crystallizable fragment (Fc) region of immunoglobulin G (IgG), and bridge humoral and cellular immunity. FcγRIIA and FcγRIIB have opposing roles, with the former responsible for activation and the...

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Veröffentlicht in:	Journal of proteome research 2024-08, Vol.23 (8), p.3469-3483
Hauptverfasser:	Abdoollah, Zaraah, Marrero Roche, Daniel E, Pavan, Carlos H, Moore, Erika, Chandler, Kevin Brown
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Glycosylation Humans Mice Polysaccharides - chemistry Polysaccharides - metabolism Receptors, IgG - chemistry Receptors, IgG - genetics Receptors, IgG - metabolism Recombinant Proteins - chemistry Recombinant Proteins - genetics Recombinant Proteins - metabolism
Online-Zugang:	Volltext
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