Proinflammatory Activation of Monocytes in Patients with Immunoinflammatory Rheumatic Diseases

The pathogenesis of immunoinflammatory rheumatic diseases (IRDs) is based on chronic inflammation, one of the key mechanisms of which may be abnormal activation of macrophages, leading to further disruption of the immune system. Objective . The objective of this study was to evaluate the proinflamma...

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Veröffentlicht in:	Doklady. Biochemistry and biophysics 2024-08, Vol.517 (1), p.228-234
Hauptverfasser:	Bogatyreva, A. I., Gerasimova, E. V., Kirichenko, T. V., Markina, Yu. V., Popkova, T. V., Shalygina, M. V., Tolstik, T. V., Markin, A. M., Orekhov, A. N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Arthritis, Rheumatoid - immunology Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biophysics Cell activation Chemokine CCL2 - metabolism Chemokines Cytokines Cytokines - metabolism Enzyme-linked immunosorbent assay Female Humans IL-1β Immune response Immunomagnetic separation Inflammation Inflammation - immunology Inflammation - metabolism Interleukin-1beta - metabolism Life Sciences Lipopolysaccharides Lipopolysaccharides - pharmacology Lupus Erythematosus, Systemic - immunology Lupus Erythematosus, Systemic - metabolism Macrophages Male Middle Aged Molecular Biology Monocyte chemoattractant protein Monocyte chemoattractant protein 1 Monocytes Monocytes - immunology Monocytes - metabolism Pathogenesis Rheumatic diseases Rheumatic Diseases - immunology Rheumatoid arthritis Scleroderma Scleroderma, Systemic - immunology Scleroderma, Systemic - metabolism Secretions Systemic lupus erythematosus Systemic sclerosis Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factor-TNF Tumor necrosis factor-α
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