Effects of different lipid sources on performance, blood lipid parameters, immune system activity, and expression of TNFα and TLR4 genes in broiler chickens
This study aimed to explore the effects of different lipid sources on the performance, blood lipid parameters, immune system activity, and the expression of TNFα and TLR4 genes in broiler chickens. A total of 500 one-day-old male chicks of the ROSS 308 commercial strain were allocated into four trea...
Gespeichert in:
| Veröffentlicht in: | Prostaglandins & other lipid mediators 2024-10, Vol.174, p.106873, Article 106873 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | 106873 |
| container_title | Prostaglandins & other lipid mediators |
| container_volume | 174 |
| creator | Ghanbari, Mojtaba Mousavi, Seyed Naser Chamani, Mohammad |
| description | This study aimed to explore the effects of different lipid sources on the performance, blood lipid parameters, immune system activity, and the expression of TNFα and TLR4 genes in broiler chickens. A total of 500 one-day-old male chicks of the ROSS 308 commercial strain were allocated into four treatment groups with five replicates each (each replicate comprised of 25 chickens), following a randomized design. The treatments were as follows: (1) a diet incorporating palm oil (PO, a source of saturated fatty acids); (2) a diet incorporating flaxseed oil (FO, a source of omega-3); (3) a diet incorporating soybean oil (SO, a source of omega-6); and (4) a diet incorporating olive oil (OO, a source of omega-9). According to the findings, the broiler chickens exhibited a significant increase in body weight gain (BWG) throughout the study when their diet consisted of unsaturated oils, as opposed to a diet including PO. Conversely, the feed conversion ratio (FCR) significantly decreased (P |
| doi_str_mv | 10.1016/j.prostaglandins.2024.106873 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3079956340</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1098882324000674</els_id><sourcerecordid>3079956340</sourcerecordid><originalsourceid>FETCH-LOGICAL-c257t-7e8438d008a6aa4c1dace25ac92cdb2d05b3e8c9eb9acb9869ba43b91564718d3</originalsourceid><addsrcrecordid>eNqNkU2OEzEQhb0AMcPAFZAXLFgkwW73jy2xQaMJIEUgobC2_FM9OHS7G5d7RA7DIbgIZ8JDAhI7Vi65XtWz30fIc842nPH25WEzpwmzuR1M9CHipmJVXVqt7MQDcsmZkmspK3FBHiMeGKsY5-wRuRCq1B3rLsn3m74Hl5FOPfWh1AlipkOYg6c4LclBaUU6Q-qnNJroYEXtME3-rJlNMiNkSLiiYRyXCBSPmGGkxuVwF_JxRcvbKHybEyCGsqs47d9vf_74fb_ffazpLcRiEyK1aQoDJOo-B_cFIj4hD3szIDw9n1fk0_Zmf_12vfvw5t31693aVU2X1x3IWkjPmDStMbXj3jioGuNU5bytPGusAOkUWGWcVbJV1tTCKt60dcelF1fkxWlvifPrApj1GNDBUGKFaUEtWKdU04qaFemrk9SV5DFBr-cURpOOmjN9D0Uf9L9Q9D0UfYJSxp-dnRY7gv87_IdIEWxPAij_vQuQNLoAJXcfUgGl_RT-z-kXzjaswg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3079956340</pqid></control><display><type>article</type><title>Effects of different lipid sources on performance, blood lipid parameters, immune system activity, and expression of TNFα and TLR4 genes in broiler chickens</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Ghanbari, Mojtaba ; Mousavi, Seyed Naser ; Chamani, Mohammad</creator><creatorcontrib>Ghanbari, Mojtaba ; Mousavi, Seyed Naser ; Chamani, Mohammad</creatorcontrib><description>This study aimed to explore the effects of different lipid sources on the performance, blood lipid parameters, immune system activity, and the expression of TNFα and TLR4 genes in broiler chickens. A total of 500 one-day-old male chicks of the ROSS 308 commercial strain were allocated into four treatment groups with five replicates each (each replicate comprised of 25 chickens), following a randomized design. The treatments were as follows: (1) a diet incorporating palm oil (PO, a source of saturated fatty acids); (2) a diet incorporating flaxseed oil (FO, a source of omega-3); (3) a diet incorporating soybean oil (SO, a source of omega-6); and (4) a diet incorporating olive oil (OO, a source of omega-9). According to the findings, the broiler chickens exhibited a significant increase in body weight gain (BWG) throughout the study when their diet consisted of unsaturated oils, as opposed to a diet including PO. Conversely, the feed conversion ratio (FCR) significantly decreased (P<0.01). The treatment with FO resulted in the highest percentage of lymphocytes and antibody titers against Newcastle and Gumboro diseases, showing a significant difference compared to the treatment with PO (P<0.01). Moreover, the relative expression of TNFα and TLR4 genes was the lowest following the FO treatment, indicating a significant decrease compared to the treatment with PO. Overall, the present findings demonstrated that incorporating omega-3 fatty acids into the diet was more effective in enhancing the growth performance, immune system, and health of broiler chickens.
•The blood lipid parameters were further improved by the use of omega-3 PUFA sources.•The omega-3 sources, in comparison to omega-6, omega-9, and SFAs, are more effective in enhancing the immune system of broiler chickens.•The omega-3 PUFAs are associated with anti-inflammatory effects, which is in stark contrast to omega-6 PUFAs, inducing inflammatory responses.</description><identifier>ISSN: 1098-8823</identifier><identifier>DOI: 10.1016/j.prostaglandins.2024.106873</identifier><identifier>PMID: 39002707</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Animal Feed - analysis ; Animals ; Broiler ; Chickens - immunology ; Fatty acids ; Fatty Acids, Omega-3 - pharmacology ; Gene Expression Regulation - drug effects ; Immune System - drug effects ; Immune System - metabolism ; Linseed Oil - pharmacology ; Lipids - blood ; Male ; Palm Oil - pharmacology ; Soybean Oil - pharmacology ; TLR-4 ; TNF-α ; Toll-Like Receptor 4 - genetics ; Toll-Like Receptor 4 - metabolism ; Tumor Necrosis Factor-alpha - genetics ; Tumor Necrosis Factor-alpha - metabolism</subject><ispartof>Prostaglandins & other lipid mediators, 2024-10, Vol.174, p.106873, Article 106873</ispartof><rights>2024 Elsevier Inc.</rights><rights>Copyright © 2024 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c257t-7e8438d008a6aa4c1dace25ac92cdb2d05b3e8c9eb9acb9869ba43b91564718d3</cites><orcidid>0009-0009-7850-3189 ; 0000-0002-4073-3597 ; 0000-0001-9244-9494</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.prostaglandins.2024.106873$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27922,27923,45993</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39002707$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ghanbari, Mojtaba</creatorcontrib><creatorcontrib>Mousavi, Seyed Naser</creatorcontrib><creatorcontrib>Chamani, Mohammad</creatorcontrib><title>Effects of different lipid sources on performance, blood lipid parameters, immune system activity, and expression of TNFα and TLR4 genes in broiler chickens</title><title>Prostaglandins & other lipid mediators</title><addtitle>Prostaglandins Other Lipid Mediat</addtitle><description>This study aimed to explore the effects of different lipid sources on the performance, blood lipid parameters, immune system activity, and the expression of TNFα and TLR4 genes in broiler chickens. A total of 500 one-day-old male chicks of the ROSS 308 commercial strain were allocated into four treatment groups with five replicates each (each replicate comprised of 25 chickens), following a randomized design. The treatments were as follows: (1) a diet incorporating palm oil (PO, a source of saturated fatty acids); (2) a diet incorporating flaxseed oil (FO, a source of omega-3); (3) a diet incorporating soybean oil (SO, a source of omega-6); and (4) a diet incorporating olive oil (OO, a source of omega-9). According to the findings, the broiler chickens exhibited a significant increase in body weight gain (BWG) throughout the study when their diet consisted of unsaturated oils, as opposed to a diet including PO. Conversely, the feed conversion ratio (FCR) significantly decreased (P<0.01). The treatment with FO resulted in the highest percentage of lymphocytes and antibody titers against Newcastle and Gumboro diseases, showing a significant difference compared to the treatment with PO (P<0.01). Moreover, the relative expression of TNFα and TLR4 genes was the lowest following the FO treatment, indicating a significant decrease compared to the treatment with PO. Overall, the present findings demonstrated that incorporating omega-3 fatty acids into the diet was more effective in enhancing the growth performance, immune system, and health of broiler chickens.
•The blood lipid parameters were further improved by the use of omega-3 PUFA sources.•The omega-3 sources, in comparison to omega-6, omega-9, and SFAs, are more effective in enhancing the immune system of broiler chickens.•The omega-3 PUFAs are associated with anti-inflammatory effects, which is in stark contrast to omega-6 PUFAs, inducing inflammatory responses.</description><subject>Animal Feed - analysis</subject><subject>Animals</subject><subject>Broiler</subject><subject>Chickens - immunology</subject><subject>Fatty acids</subject><subject>Fatty Acids, Omega-3 - pharmacology</subject><subject>Gene Expression Regulation - drug effects</subject><subject>Immune System - drug effects</subject><subject>Immune System - metabolism</subject><subject>Linseed Oil - pharmacology</subject><subject>Lipids - blood</subject><subject>Male</subject><subject>Palm Oil - pharmacology</subject><subject>Soybean Oil - pharmacology</subject><subject>TLR-4</subject><subject>TNF-α</subject><subject>Toll-Like Receptor 4 - genetics</subject><subject>Toll-Like Receptor 4 - metabolism</subject><subject>Tumor Necrosis Factor-alpha - genetics</subject><subject>Tumor Necrosis Factor-alpha - metabolism</subject><issn>1098-8823</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU2OEzEQhb0AMcPAFZAXLFgkwW73jy2xQaMJIEUgobC2_FM9OHS7G5d7RA7DIbgIZ8JDAhI7Vi65XtWz30fIc842nPH25WEzpwmzuR1M9CHipmJVXVqt7MQDcsmZkmspK3FBHiMeGKsY5-wRuRCq1B3rLsn3m74Hl5FOPfWh1AlipkOYg6c4LclBaUU6Q-qnNJroYEXtME3-rJlNMiNkSLiiYRyXCBSPmGGkxuVwF_JxRcvbKHybEyCGsqs47d9vf_74fb_ffazpLcRiEyK1aQoDJOo-B_cFIj4hD3szIDw9n1fk0_Zmf_12vfvw5t31693aVU2X1x3IWkjPmDStMbXj3jioGuNU5bytPGusAOkUWGWcVbJV1tTCKt60dcelF1fkxWlvifPrApj1GNDBUGKFaUEtWKdU04qaFemrk9SV5DFBr-cURpOOmjN9D0Uf9L9Q9D0UfYJSxp-dnRY7gv87_IdIEWxPAij_vQuQNLoAJXcfUgGl_RT-z-kXzjaswg</recordid><startdate>202410</startdate><enddate>202410</enddate><creator>Ghanbari, Mojtaba</creator><creator>Mousavi, Seyed Naser</creator><creator>Chamani, Mohammad</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0009-0009-7850-3189</orcidid><orcidid>https://orcid.org/0000-0002-4073-3597</orcidid><orcidid>https://orcid.org/0000-0001-9244-9494</orcidid></search><sort><creationdate>202410</creationdate><title>Effects of different lipid sources on performance, blood lipid parameters, immune system activity, and expression of TNFα and TLR4 genes in broiler chickens</title><author>Ghanbari, Mojtaba ; Mousavi, Seyed Naser ; Chamani, Mohammad</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c257t-7e8438d008a6aa4c1dace25ac92cdb2d05b3e8c9eb9acb9869ba43b91564718d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Animal Feed - analysis</topic><topic>Animals</topic><topic>Broiler</topic><topic>Chickens - immunology</topic><topic>Fatty acids</topic><topic>Fatty Acids, Omega-3 - pharmacology</topic><topic>Gene Expression Regulation - drug effects</topic><topic>Immune System - drug effects</topic><topic>Immune System - metabolism</topic><topic>Linseed Oil - pharmacology</topic><topic>Lipids - blood</topic><topic>Male</topic><topic>Palm Oil - pharmacology</topic><topic>Soybean Oil - pharmacology</topic><topic>TLR-4</topic><topic>TNF-α</topic><topic>Toll-Like Receptor 4 - genetics</topic><topic>Toll-Like Receptor 4 - metabolism</topic><topic>Tumor Necrosis Factor-alpha - genetics</topic><topic>Tumor Necrosis Factor-alpha - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ghanbari, Mojtaba</creatorcontrib><creatorcontrib>Mousavi, Seyed Naser</creatorcontrib><creatorcontrib>Chamani, Mohammad</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Prostaglandins & other lipid mediators</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ghanbari, Mojtaba</au><au>Mousavi, Seyed Naser</au><au>Chamani, Mohammad</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of different lipid sources on performance, blood lipid parameters, immune system activity, and expression of TNFα and TLR4 genes in broiler chickens</atitle><jtitle>Prostaglandins & other lipid mediators</jtitle><addtitle>Prostaglandins Other Lipid Mediat</addtitle><date>2024-10</date><risdate>2024</risdate><volume>174</volume><spage>106873</spage><pages>106873-</pages><artnum>106873</artnum><issn>1098-8823</issn><abstract>This study aimed to explore the effects of different lipid sources on the performance, blood lipid parameters, immune system activity, and the expression of TNFα and TLR4 genes in broiler chickens. A total of 500 one-day-old male chicks of the ROSS 308 commercial strain were allocated into four treatment groups with five replicates each (each replicate comprised of 25 chickens), following a randomized design. The treatments were as follows: (1) a diet incorporating palm oil (PO, a source of saturated fatty acids); (2) a diet incorporating flaxseed oil (FO, a source of omega-3); (3) a diet incorporating soybean oil (SO, a source of omega-6); and (4) a diet incorporating olive oil (OO, a source of omega-9). According to the findings, the broiler chickens exhibited a significant increase in body weight gain (BWG) throughout the study when their diet consisted of unsaturated oils, as opposed to a diet including PO. Conversely, the feed conversion ratio (FCR) significantly decreased (P<0.01). The treatment with FO resulted in the highest percentage of lymphocytes and antibody titers against Newcastle and Gumboro diseases, showing a significant difference compared to the treatment with PO (P<0.01). Moreover, the relative expression of TNFα and TLR4 genes was the lowest following the FO treatment, indicating a significant decrease compared to the treatment with PO. Overall, the present findings demonstrated that incorporating omega-3 fatty acids into the diet was more effective in enhancing the growth performance, immune system, and health of broiler chickens.
•The blood lipid parameters were further improved by the use of omega-3 PUFA sources.•The omega-3 sources, in comparison to omega-6, omega-9, and SFAs, are more effective in enhancing the immune system of broiler chickens.•The omega-3 PUFAs are associated with anti-inflammatory effects, which is in stark contrast to omega-6 PUFAs, inducing inflammatory responses.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>39002707</pmid><doi>10.1016/j.prostaglandins.2024.106873</doi><orcidid>https://orcid.org/0009-0009-7850-3189</orcidid><orcidid>https://orcid.org/0000-0002-4073-3597</orcidid><orcidid>https://orcid.org/0000-0001-9244-9494</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1098-8823 |
| ispartof | Prostaglandins & other lipid mediators, 2024-10, Vol.174, p.106873, Article 106873 |
| issn | 1098-8823 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_3079956340 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Animal Feed - analysis Animals Broiler Chickens - immunology Fatty acids Fatty Acids, Omega-3 - pharmacology Gene Expression Regulation - drug effects Immune System - drug effects Immune System - metabolism Linseed Oil - pharmacology Lipids - blood Male Palm Oil - pharmacology Soybean Oil - pharmacology TLR-4 TNF-α Toll-Like Receptor 4 - genetics Toll-Like Receptor 4 - metabolism Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - metabolism |
| title | Effects of different lipid sources on performance, blood lipid parameters, immune system activity, and expression of TNFα and TLR4 genes in broiler chickens |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T22%3A55%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20different%20lipid%20sources%20on%20performance,%20blood%20lipid%20parameters,%20immune%20system%20activity,%20and%20expression%20of%20TNF%CE%B1%20and%20TLR4%20genes%20in%20broiler%20chickens&rft.jtitle=Prostaglandins%20&%20other%20lipid%20mediators&rft.au=Ghanbari,%20Mojtaba&rft.date=2024-10&rft.volume=174&rft.spage=106873&rft.pages=106873-&rft.artnum=106873&rft.issn=1098-8823&rft_id=info:doi/10.1016/j.prostaglandins.2024.106873&rft_dat=%3Cproquest_cross%3E3079956340%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3079956340&rft_id=info:pmid/39002707&rft_els_id=S1098882324000674&rfr_iscdi=true |