Effect of Isoscopoletin on Cytokine Expression in HaCaT Keratinocytes and RBL-2H3 Basophils: Preliminary Study

Isoscopoletin is a compound derived from various plants traditionally used for the treatment of skin diseases. However, there have been no reported therapeutic effects of isoscopoletin on atopic dermatitis (AD). AD is a chronic inflammatory skin disease, and commonly used treatments have side effect...

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Veröffentlicht in:	International journal of molecular sciences 2024-07, Vol.25 (13), p.6908
Hauptverfasser:	Seo, Da-Yun, Park, Ji-Won, Kim, Seung-Ho, Oh, Sei-Ryang, Han, Sang-Bae, Kwon, Ok-Kyoung, Ahn, Kyung-Seop
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Basophils - drug effects Basophils - metabolism Cell Line Cell Survival - drug effects Chemokines Chronic illnesses Cytokines Cytokines - metabolism Dermatitis, Atopic - drug therapy Dermatitis, Atopic - metabolism Gene Expression Regulation - drug effects HaCaT Cells Humans Interferon-gamma - metabolism Interferon-gamma - pharmacology Keratinocytes - drug effects Keratinocytes - metabolism Kinases Morphology Phosphorylation Proteins Signal Transduction - drug effects Skin diseases Steroids Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factor-TNF
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