Boosting the Anti‐Helicobacter Efficacy of Azithromycin through Natural Compounds: Insights From In Vitro, In Vivo, Histopathological, and Molecular Docking Investigations

ABSTRACT Background Antimicrobial‐resistant Helicobacter pylori (H. pylori) poses a significant public health concern, especially given the limited therapeutic options for azithromycin‐resistant strains. Hence, there is a necessity for new studies to reconsider the use of azithromycin, which has dim...

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Veröffentlicht in:	Helicobacter (Cambridge, Mass.) Mass.), 2024-07, Vol.29 (4), p.e13110-n/a
Hauptverfasser:	Bendary, Mahmoud M., Elmanakhly, Arwa R., Mosallam, Farag M., Alblwi, Noaf Abdullah N., Mosbah, Rasha A., Alshareef, Walaa A., Selim, Heba M. R. M., Alhomrani, Majid, Alamri, Abdulhakeem S., Safwat, Nesreen A., Hamdan, Ahmed M. E., Elshimy, Rana
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antibiotics anti‐biofilm anti‐Helicobacter anti‐virulence Azithromycin Azithromycin - chemistry Azithromycin - pharmacology Biofilms Biofilms - drug effects Biological Products - chemistry Biological Products - pharmacology Curcumin Curcumin - chemistry Curcumin - pharmacology curcumin nanoemulsion Drug development Drug Synergism Effectiveness Emulsions Female FICI Formulations Genes H. pylori Helicobacter Helicobacter Infections - drug therapy Helicobacter Infections - microbiology Helicobacter pylori - drug effects Helicobacter pylori - genetics In vivo methods and tests Mice Microbial Sensitivity Tests Minimum inhibitory concentration Molecular docking Molecular Docking Simulation Nanoemulsions Protein folding Public health Strains (organisms) Synergistic effect Urea Virulence Virulence - drug effects
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