Cholinesterase Inhibition and Antioxidative Capacity of New Heteroaromatic Resveratrol Analogs: Synthesis and Physico-Chemical Properties

The targeted compounds in this research, resveratrol analogs - , were synthesized as mixtures of isomers by the Wittig reaction using heterocyclic triphenylphosphonium salts and various benzaldehydes. The planned compounds were those possessing the -configuration as the biologically active -resverat...

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Veröffentlicht in:	International journal of molecular sciences 2024-07, Vol.25 (13), p.7401
Hauptverfasser:	Mlakić, Milena, Talić, Stanislava, Odak, Ilijana, Barić, Danijela, Šagud, Ivana, Škorić, Irena
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase - chemistry Acetylcholinesterase - metabolism Antioxidants Antioxidants - chemical synthesis Antioxidants - chemistry Antioxidants - pharmacology Biological activity Butyrylcholinesterase - chemistry Butyrylcholinesterase - metabolism Cholinesterase Inhibitors - chemical synthesis Cholinesterase Inhibitors - chemistry Cholinesterase Inhibitors - pharmacology Enzymes Free radicals Humans Hydrogen bonds Investigations Molecular Docking Simulation Polyphenols Resveratrol - analogs & derivatives Resveratrol - chemical synthesis Resveratrol - chemistry Resveratrol - pharmacology Structure-Activity Relationship
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