Efficacy and safety of androgen receptor inhibitors for treatment of advanced prostate cancer: A systematic review and network meta‐analysis

Aims Androgen receptor inhibitors (ARIs) have become an effective treatment for advanced prostate cancer (PC). However, it is unknown which ARI is the most helpful and safe for men with advanced PC. Our aim is to help physicians make clinical decisions and provide medication guidelines for patients...

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Veröffentlicht in:	British journal of clinical pharmacology 2024-09, Vol.90 (9), p.2067-2078
Hauptverfasser:	Xiao, Shichao, Yin, Hang, Lv, Xin, Wang, Zhen, Jiang, Lili, Xia, Yangliu, Liu, Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	advanced prostate cancer adverse events Androgen Antagonists - administration & dosage Androgen Antagonists - adverse effects Androgen Antagonists - therapeutic use Androgen Receptor Antagonists - administration & dosage Androgen Receptor Antagonists - adverse effects Androgen Receptor Antagonists - therapeutic use androgen receptor inhibitors Benzamides - administration & dosage Benzamides - adverse effects Benzamides - therapeutic use Flutamide - administration & dosage Flutamide - adverse effects Flutamide - therapeutic use Humans Male Network Meta-Analysis Nitriles - administration & dosage Nitriles - adverse effects Nitriles - therapeutic use overall survival Phenylthiohydantoin - administration & dosage Phenylthiohydantoin - adverse effects Phenylthiohydantoin - therapeutic use Prostatic Neoplasms - drug therapy Prostatic Neoplasms - mortality Thiohydantoins - administration & dosage Thiohydantoins - adverse effects Thiohydantoins - therapeutic use Treatment Outcome
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