Self-Assembly of Ultrasmall 3D Architectures of (l)‑Acyclic Threoninol Nucleic Acids with High Thermal and Serum Stability

The primary challenge of implementing DNA nanostructures in biomedical applications lies in their vulnerability to nuclease degradation and variations in ionic strength. Furthermore, the size minimization of DNA and RNA nanostructures is limited by the stability of the DNA and RNA duplexes. This stu...

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Veröffentlicht in:	Journal of the American Chemical Society 2024-07, Vol.146 (29), p.20141-20146
Hauptverfasser:	Skaanning, Mads K., Bønnelykke, Jonas, Nijenhuis, Minke A. D., Samanta, Anirban, Smidt, Jakob Melgaard, Gothelf, Kurt V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Alcohols - chemistry Butylene Glycols - chemistry DNA - chemistry Humans Nanostructures - chemistry Nucleic Acid Conformation Nucleic Acids - chemistry Temperature
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