Preparation of nanoparticle and nanoemulsion formulations containing repaglinide and determination of pharmacokinetic parameters in rats

Repaglinide (RPG) belongs to the class of drugs known as meglitinides and is used for improving and maintaining glycemic control in the treatment of patients with Type 2 diabetes. RPG is a Class II drug (BCS) because of its high permeability and low water solubility. It also undergoes hepatic first-...

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Veröffentlicht in:	European journal of pharmaceutical sciences 2024-09, Vol.200, p.106844, Article 106844
Hauptverfasser:	Demirturk, Esra, Ugur Kaplan, Afife Busra, Cetin, Meltem, Dönmez Kutlu, Meltem, Köse, Seda, Akıllıoğlu, Kübra
Format:	Artikel
Sprache:	eng
Schlagworte:	Nanoemulsion Nanoparticle Oral administration Pharmacokinetic study Repaglinide
Online-Zugang:	Volltext
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