Biphasic co-detection of melanoma aneuploid tumor cells and tumor endothelial cells in guidance of specifying the field cancerized surgical excision margin and administering immunotherapy

An optimum safety excision margin (EM) delineated by precise demarcation of field cancerization along with reliable biomarkers that enable predicting and timely evaluating patients’ response to immunotherapy significantly impact effective management of melanoma. In this study, optimized biphasic “im...

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Veröffentlicht in:	Cancer letters 2024-08, Vol.598, p.217099, Article 217099
Hauptverfasser:	Fu, Zhengzheng, Zhang, Lina, Chen, Rongyi, Zhan, Jipang, Zhong, Jing, Zheng, Wen, Zou, Jingwen, Wang, Peng, Deng, Xiaohua, Lin, Alexander Y., Wang, Daisy Dandan, Lin, Peter Ping, He, Renliang
Format:	Artikel
Sprache:	eng
Schlagworte:	Aneuploid CTCs and CTECs Cellular MRD iFISH tumor tissue and liquid biopsies Quantified field cancerization Safety excision margin
Online-Zugang:	Volltext
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