Exosomal miR-196b secreted from bronchial epithelial cells chronically exposed to low-dose PM2.5 promotes invasiveness of adjacent and lung cancer cells

Fine particulate matter (PM2.5) is a risk factor for pulmonary diseases and lung cancer, and inhaled PM2.5 is mainly deposited in the bronchial epithelium. In this study, we investigated the effect of long-term exposure to low-dose PM2.5 on BEAS-2B cells derived from the normal bronchial epithelium....

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Veröffentlicht in:	Toxicology letters 2024-08, Vol.399, p.9-18
Hauptverfasser:	Yu, Seong-Lan, Koo, Han, Kang, Yujin, Jeon, Hye Jin, Kang, Minho, Choi, Dong Hee, Lee, Su Yel, Son, Ji Woong, Lee, Dong Chul
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell invasion Epithelial-mesenchymal transition Exosome MiR-196b-5p Particulate matter
Online-Zugang:	Volltext
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