SARS-CoV-2 inhibitory potential of fish oil-derived 2-pyrone compounds by acquiring linoleic acid binding site on the spike protein

Traditional medicines have reportedly treated SARS-CoV-2 infection. Substantial evidence shows that fish oil supplements promote human immune function, suggesting they may lessen susceptibility to SARS-CoV-2 infection and suppress viral replication by inducing interferon. Fish oil was subjected to p...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of biological macromolecules 2024-08, Vol.275 (Pt 1), p.133634, Article 133634
Hauptverfasser:	Duragkar, Nandkishor, Chikhale, Rupesh, Piechota, Malgorzata, Danta, Chhanda Charan, Gandhale, Pradeep, Itankar, Prakash, Chikhale, Sonali, Gurav, Nilambari, Khan, Mohd Shahnawaz, Pokrzywa, Wojciech, Thapa, Pankaj, Bryce, Richard, Gurav, Shailendra
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Antiviral Agents - chemistry Antiviral Agents - pharmacology Binding Sites COVID-19 - virology COVID-19 Drug Treatment Fatty acids Fish oil Fish Oils - chemistry Fish Oils - pharmacology Humans In-silico studies Linoleic Acid - chemistry Linoleic Acid - pharmacology Molecular Docking Simulation Molecular Dynamics Simulation Pyrones - chemistry Pyrones - pharmacology RBD-domain SARS-CoV-2 SARS-CoV-2 - drug effects Spike Glycoprotein, Coronavirus - chemistry Spike Glycoprotein, Coronavirus - metabolism Spike protein TMPRSS2
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!