Exploring the role of vitamin D-VDR pathway in pemphigus foliaceous: a novel perspective on disease pathogenesis

Several auto-immune diseases have been linked to vitamin D deficiency as a contributing environmental factor. Its pleiotropic effects on the immune system, especially its essential role in maintaining immune tolerance, make the vitamin D pathway of great interest. In this study, we focused on Pemphi...

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Veröffentlicht in:	Archives of dermatological research 2024-07, Vol.316 (7), p.449, Article 449
Hauptverfasser:	Tahri, Safa, Elloumi, Nesrine, Khabou, Boudour, Frikha, Rim, Turki, Hamida, Mahfoudh, Nadia, Bahloul, Emna, Hachicha, Hend, Masmoudi, Hatem, Abida, Olfa
Format:	Artikel
Sprache:	eng
Schlagworte:	25-Hydroxyvitamin D3 1-alpha-Hydroxylase - genetics 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - metabolism Adult Aged Autoimmune diseases Blood cells Case-Control Studies Chemiluminescence Dermatology Environmental factors Female Gene expression Genes Genetic analysis Genetic Predisposition to Disease Haplotypes Humans Immune system Immunological diseases Immunological tolerance Male Medicine Medicine & Public Health Middle Aged Original Paper Pemphigus Pemphigus - diagnosis Pemphigus - genetics Pemphigus - immunology Polymorphism, Single Nucleotide Population studies Receptors, Calcitriol - genetics Receptors, Calcitriol - metabolism Remission Skin - immunology Skin - metabolism Skin - pathology Skin diseases Tunisia Vitamin D Vitamin D - analogs & derivatives Vitamin D - blood Vitamin D - metabolism Vitamin D Deficiency - blood Vitamin D Deficiency - complications Vitamin D Deficiency - immunology Vitamin D receptors Vitamin D3 24-Hydroxylase - genetics Vitamin D3 24-Hydroxylase - metabolism Vitamin deficiency
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