Insoluble polysaccharides produced in plant cell cultures protect from Clostridioides difficile colitis

Clostridioides difficile infection (CDI) poses a significant health threat due to high recurrence rates. Antimicrobial agents are commonly used to manage CDI-related diarrhoea; however, by aggravating intestinal dysbiosis, antibiotics enable C. difficile spores germination and production of toxins,...

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Veröffentlicht in:	Microbiological research 2024-09, Vol.286, p.127812, Article 127812
Hauptverfasser:	Bernabè, Giulia, Castagliuolo, Ignazio, Porzionato, Andrea, Casarotto, Gino, Monte, Renzo Dal, Carpi, Andrea, Brun, Paola
Format:	Artikel
Sprache:	eng
Schlagworte:	adsorbents animal models body weight changes Clostridium difficile colitis cytotoxicity diarrhea Diarrhoea drug therapy dysbiosis exotoxins germination Gut humans inflammation Insoluble polysaccharides intestinal microorganisms intestines myeloperoxidase polysaccharides species Toxins virulence wheat bran
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