Oral smoothened inhibitors for Gorlin syndrome: A clinical review

Although smoothened inhibitors (SMOi) have demonstrated efficacy in the management of basal cell carcinoma, no guidelines are available on how to utilize SMOi in the treatment of Gorlin syndrome (GS). This review's objective is to assess the clinical response to SMOi in GS, provide practical gu...

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Veröffentlicht in:	Journal of the American Academy of Dermatology 2024-10, Vol.91 (4), p.706-711
Hauptverfasser:	Baczynski, Alexandra, Cahn, Brian, Worley, Brandon, Haber, Roger, Alam, Murad
Format:	Artikel
Sprache:	eng
Schlagworte:	Gorlin syndrome Hedgehog inhibitors Nevoid basal cell carcinoma syndrome oral smoothened inhibitors smoothened inhibitors sonidegib systemic therapy vismodegib
Online-Zugang:	Volltext
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