Quantification of treprostinil concentration in rat and human using a novel validated and rapid liquid chromatography-tandem mass spectrometry method: Experimental and clinical applications in ischemia–reperfusion injury

Overview of biological sample preparation and quantification of treprostinil by LC-MS/MS. [Display omitted] •Renal ischemia–reperfusion injury (IRI) is inevitable during kidney transplantation with no approved therapy.•Treprostinil, a prostacyclin analog, is a potential therapy to treat renal IRI.•A...

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Veröffentlicht in:	Clinica chimica acta 2024-07, Vol.561, p.119837, Article 119837
Hauptverfasser:	Gallucci, Gina M., Agbabiaka, Mariam Oladepo, Ding, Meiwen, Gohh, Reginald, Ghonem, Nisanne S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Ischemia-reperfusion Injury Kidney transplantation Liquid chromatography-mass spectrometry Prostacyclin Treprostinil
Online-Zugang:	Volltext
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