Application of cell-free DNA fungal polymerase chain reaction for invasive fungal disease evaluation in pediatric oncology and stem cell transplant patients

Molecular diagnostics may enable early, noninvasive detection of invasive fungal disease (IFD) in immunocompromised patients. Cell-free deoxyribonucleic acid (cfDNA) fungal polymerase chain reaction (PCR) assays were recently incorporated into institutional prolonged febrile neutropenia pathways. We...

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Veröffentlicht in:	Pediatric blood & cancer 2024-09, Vol.71 (9), p.e31133
Hauptverfasser:	Kushner, Lauren E, Schwenk, Hayden T, Qin, FeiFei, Boothroyd, Derek, Aftandilian, Catherine
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Cell-Free Nucleic Acids - blood Child Child, Preschool DNA, Fungal - blood Female Follow-Up Studies Fungal diseases Hematopoietic Stem Cell Transplantation Hematopoietic stem cells Humans Immunocompromised Host Immunocompromised hosts Infant Invasive Fungal Infections - diagnosis Male Mold Neoplasms - blood Neutropenia Oncology Patients Pediatrics Performance evaluation Plasma Polymerase chain reaction Polymerase Chain Reaction - methods Prognosis Stem cell transplantation Survival Rate
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