Anticonvulsant and anxiolytic-like potential of the essential oil from the Ocimum basilicum Linn leaves and its major constituent estragole on adult zebrafish (Danio rerio)

The Ocimum species present active compounds with the potential to develop drugs for treating chronic disease conditions, such as anxiety and seizures. The present study aims to investigate the anticonvulsant and anxiolytic-like effect of the essential oil from O. basilicum Linn (OEFOb) leaves and it...

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Veröffentlicht in:	Neurochemistry international 2024-09, Vol.178, p.105796, Article 105796
Hauptverfasser:	Batista, Francisco Lucas A., de Araújo, Sandra Maria B., de Sousa, Daniela Braga, Sobrinho, Francisco Bastos C., de Lima Silva, Maria Gabriely, de Oliveira, Maria Rayane C., da Costa, Roger Henrique S., Rodrigues, Lindaiane Bezerra, Bezerra, Franciglauber Silva, de Azevedo, Djane Ventura, Vieira-Neto, Antônio Eufrásio, Magalhães, Francisco Ernani A., de Menezes, Irwin Rose Alencar
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult zebrafish (Danio rerio) Allylbenzene Derivatives - pharmacology Animals Anisoles - isolation & purification Anisoles - pharmacology Anti-Anxiety Agents - chemistry Anti-Anxiety Agents - isolation & purification Anti-Anxiety Agents - pharmacology Anticonvulsants - chemistry Anticonvulsants - isolation & purification Anticonvulsants - pharmacology Anxiety Anxiety - drug therapy Convulsion Essential oil Estragole Leaves from Ocimum basilicum Male Molecular Docking Simulation Ocimum basilicum - chemistry Oils, Volatile - chemistry Oils, Volatile - isolation & purification Oils, Volatile - pharmacology Pentylenetetrazole - toxicity Plant Leaves - chemistry Seizures - chemically induced Seizures - drug therapy Zebrafish
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