Mef2d potentiates type-2 immune responses and allergic lung inflammation

Innate lymphoid cells (ILCs) and adaptive T lymphocytes promote tissue homeostasis and protective immune responses. Their production depends on the transcription factor GATA3, which is further elevated specifically in ILC2s and T helper 2 cells to drive type-2 immunity during tissue repair, allergic...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 2024-06, Vol.384 (6703), p.eadl0370
Hauptverfasser:	Szeto, Aydan C H, Clark, Paula A, Ferreira, Ana C F, Heycock, Morgan, Griffiths, Emma L, Jou, Eric, Mannion, Jonathan, Luan, Shi-Lu, Storrar, Sophie, Knolle, Martin D, Kozik, Patrycja, Jolin, Helen E, Fallon, Padraic G, McKenzie, Andrew N J
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens - immunology Allergies Animal models Animals Antibodies Antiparasitic agents Boolean Calcium Calcium Signaling Calcium signalling CD4 antigen Cell culture Cell Differentiation CRISPR Cytokines Deletion Dendritic cells Epitopes GATA3 Transcription Factor - genetics GATA3 Transcription Factor - metabolism Gene expression Gene regulation Genes Helper cells Hypersensitivity - immunology Immune response Immune system Immunity Immunity, Innate Individualized Instruction Inflammation Interleukin 13 Interleukin 7 receptors Interleukin-1 Receptor-Like 1 Protein Interleukin-33 - metabolism Interleukins Intracellular signalling Logic circuits Logical Thinking Lung - immunology Lungs Lymphocytes Lymphocytes - immunology Lymphocytes T Macrophages Measles MEF2 Transcription Factors - genetics MEF2 Transcription Factors - metabolism Mice Mice, Inbred C57BL NF-AT protein NFATC Transcription Factors - metabolism Pneumonia - immunology Protein folding Proteins Signal transduction Th2 Cells - immunology Therapeutic targets Transcription factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!