Similar endothelium-dependent vascular responses to intermittent hypoxia in young and older adults

Aging is associated with vascular endothelial dysfunction observed through a progressive loss of flow-mediated dilation caused partly by a decreased nitric oxide bioavailability. Intermittent hypoxia, consisting of alternating short bouts of breathing hypoxic and normoxic air, was reported to either...

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Veröffentlicht in:	Journal of applied physiology (1985) 2024-08, Vol.137 (2), p.254-261
Hauptverfasser:	Stray-Gundersen, Sten, Wojan, Frank, Tanaka, Hirofumi, Lalande, Sophie
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adults Age Age Factors Aged Aging Aging - physiology Bioavailability Brachial Artery - physiopathology Endothelium Endothelium, Vascular - physiology Endothelium, Vascular - physiopathology Female Humans Hypoxia Hypoxia - physiopathology Male Middle Aged Nitrates - blood Nitric oxide Nitric Oxide - metabolism Older people Oxygen content Regional Blood Flow - physiology Shear rate Vasodilation Vasodilation - physiology Young Adult Young adults
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