Propensity score weighted multi‐source exchangeability models for incorporating external control data in randomized clinical trials

Among clinical trialists, there has been a growing interest in using external data to improve decision‐making and accelerate drug development in randomized clinical trials (RCTs). Here we propose a novel approach that combines the propensity score weighting (PW) and the multi‐source exchangeability...

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Veröffentlicht in:	Statistics in medicine 2024-09, Vol.43 (20), p.3815-3829
Hauptverfasser:	Wei, Wei, Zhang, Yunxuan, Roychoudhury, Satrajit
Format:	Artikel
Sprache:	eng
Schlagworte:	Bayesian design Clinical decision making Clinical outcomes Clinical trials Drug development hybrid control pediatric study rare disease
Online-Zugang:	Volltext
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