Superoxide dismutase-contained solid lipid nanoparticles: Formulation development and In-vivo evaluation for second-degree burn wound healing in rats

Superoxide dismutase (SOD), a natural enzyme with high antioxidant activity, reduces injury and accelerates wound healing by scavenging superoxide radicals. This enzyme plays an important role in cellular defense against oxidative stress such as burn injury. The aim of this study was to load SOD int...

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Veröffentlicht in:	Burns 2024-09, Vol.50 (7), p.1823-1831
Hauptverfasser:	Makhmalzadeh, Behzad Sharif, Dehkordi, Siavash Khaksar Haghani, Rezaie, Anahita, Karami, Masoud Ali
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animals Antioxidants - pharmacology Burns - pathology Disease Models, Animal Granulation Tissue - drug effects Granulation Tissue - pathology Lipids Male Nanoparticles Neovascularization, Physiologic - drug effects Particle Size Rats Rats, Wistar Re-Epithelialization - drug effects Second-degree burn Solid lipid nanoparticles Superoxide dismutase Superoxide Dismutase - metabolism Superoxide Dismutase - therapeutic use Wound healing Wound Healing - drug effects
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