Inflammasomes: emerging therapeutic targets in hidradenitis suppurativa?

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by recurrent inflammatory lesions, which affect skin and hair follicles in intertriginous areas. HS has a multifactorial aetiology resulting in barrier dysfunction associated with aberrant immune activation. There is...

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Veröffentlicht in:	British journal of dermatology (1951) 2024-10, Vol.191 (5), p.670-679
Hauptverfasser:	Campbell, Ciara, Mayatra, Jay M, Neve, Ashish J, Fletcher, Jean M, Johnston, Daniel G W
Format:	Artikel
Sprache:	eng
Schlagworte:	Hidradenitis Suppurativa - drug therapy Hidradenitis Suppurativa - immunology Humans Immunotherapy - methods Inflammasomes - immunology Inflammasomes - metabolism Interleukin-1beta - antagonists & inhibitors Interleukin-1beta - immunology Interleukin-1beta - metabolism Molecular Targeted Therapy - methods NLR Family, Pyrin Domain-Containing 3 Protein - antagonists & inhibitors NLR Family, Pyrin Domain-Containing 3 Protein - metabolism Signal Transduction - drug effects Signal Transduction - immunology
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