High-dose vancomycin spacers provided early recovery without nephrotoxicity compared with standard-dose in MRSA-induced periprosthetic joint infection model of rats

Periprosthetic joint infections (PJIs) are commonly treated with two-stage revision surgery utilising antibiotic-loaded spacers; however, antibiotic release from spacers is limited and usually drops below effective levels a few days after placement. This study compared high-dose and standard-dose va...

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Veröffentlicht in:The knee 2024-08, Vol.49, p.125-134
Hauptverfasser: Ersoy, Ahmet, Say, Ferhat, Tokur, Orhan, Karaca, Efe, Aksoy, Abdurrahman, Çiftçi, Alper
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Sprache:eng
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