Association of handgrip strength asymmetry and weakness with cognitive function: a nationally representative cohort study
•Handgrip strength asymmetry with the non-dominant hand having a higher value than the dominant hand predicted accelerated cognitive decline.•Handgrip strength asymmetry with the dominant hand having a higher value than the non-dominant hand was beneficial for cognitive function.•Handgrip weakness p...
Gespeichert in:
| Veröffentlicht in: | Maturitas 2024-09, Vol.187, p.108057, Article 108057 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | 108057 |
| container_title | Maturitas |
| container_volume | 187 |
| creator | Zhang, Youyou Zhu, Rui Ge, Liru Zhang, Xiaoyue Tian, Dalong Pan, Faming Wang, Mengmeng Cai, Guoqi |
| description | •Handgrip strength asymmetry with the non-dominant hand having a higher value than the dominant hand predicted accelerated cognitive decline.•Handgrip strength asymmetry with the dominant hand having a higher value than the non-dominant hand was beneficial for cognitive function.•Handgrip weakness predicted accelerated cognitive decline.•Handgrip strength asymmetry may be used to monitor cognitive impairment.
To describe the association of handgrip strength asymmetry and weakness with cognitive function among Chinese middle-aged and older adults.
We used data from four waves (2011, 2013, 2015, and 2018) of the China Health and Retirement Longitudinal Study. Handgrip strength was measured at baseline. Handgrip strength asymmetry was defined on the basis of the ratio of handgrip strength of the non-dominant hand to that of the dominant hand (i.e. non-dominant/dominant): a ratio of 1.1 as non-dominant handgrip strength asymmetry. Weakness was defined as a handgrip strength of |
| doi_str_mv | 10.1016/j.maturitas.2024.108057 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3071282643</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S037851222400152X</els_id><sourcerecordid>3071282643</sourcerecordid><originalsourceid>FETCH-LOGICAL-c247t-e3da14525b92dbbf44dcd911cc0df7421b64140b586900d0bbb71978b0d227353</originalsourceid><addsrcrecordid>eNqFkE1v1DAQhi0EokvhL4CPXLL4K3HCbVWVD6kSFzhb_pjseknsxXZa5d_j7ZZeOY0088w7mgehD5RsKaHdp-N21mVJvui8ZYSJ2u1JK1-gDe0lbwSl9CXaEC77pqWMXaE3OR8JIS3h4jW64v1Q-Y5s0LrLOVqvi48BxxEfdHD75E84lwRhXw5Y53WeoaQV1xF-AP07QM74wdeZjfvgi78HPC7BnjM-Y43DY5qephUnOCXIEIp-pGw8xFRq9uLWt-jVqKcM757qNfr15fbnzbfm7sfX7ze7u8YyIUsD3GkqWtaagTljRiGcdQOl1hI3SsGo6QQVxLR9NxDiiDFG0kH2hjjGJG_5Nfp4yT2l-GeBXNTss4Vp0gHikhUnkrKedYJXVF5Qm2LOCUZ1Sn7WaVWUqLN3dVTP3tXZu7p4r5vvn44sZgb3vPdPdAV2FwDqq_ceksrWQ7DgfAJblIv-v0f-Ajs4m58</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3071282643</pqid></control><display><type>article</type><title>Association of handgrip strength asymmetry and weakness with cognitive function: a nationally representative cohort study</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Zhang, Youyou ; Zhu, Rui ; Ge, Liru ; Zhang, Xiaoyue ; Tian, Dalong ; Pan, Faming ; Wang, Mengmeng ; Cai, Guoqi</creator><creatorcontrib>Zhang, Youyou ; Zhu, Rui ; Ge, Liru ; Zhang, Xiaoyue ; Tian, Dalong ; Pan, Faming ; Wang, Mengmeng ; Cai, Guoqi</creatorcontrib><description>•Handgrip strength asymmetry with the non-dominant hand having a higher value than the dominant hand predicted accelerated cognitive decline.•Handgrip strength asymmetry with the dominant hand having a higher value than the non-dominant hand was beneficial for cognitive function.•Handgrip weakness predicted accelerated cognitive decline.•Handgrip strength asymmetry may be used to monitor cognitive impairment.
To describe the association of handgrip strength asymmetry and weakness with cognitive function among Chinese middle-aged and older adults.
We used data from four waves (2011, 2013, 2015, and 2018) of the China Health and Retirement Longitudinal Study. Handgrip strength was measured at baseline. Handgrip strength asymmetry was defined on the basis of the ratio of handgrip strength of the non-dominant hand to that of the dominant hand (i.e. non-dominant/dominant): a ratio of <0.9 defined as dominant handgrip strength asymmetry and >1.1 as non-dominant handgrip strength asymmetry. Weakness was defined as a handgrip strength of <28 kg for males or <18 kg for females.
Cognitive function with its two core dimensions (episodic memory and mental status) at each wave was assessed and standardized.
9333 participants (48.3 % female, age 58.2 ± 9.0 years) were included. Non-dominant but not dominant handgrip strength asymmetry was significantly associated with poorer cognitive function at baseline (β = −0.121, −0.092, and −0.132 for mental status, episodic memory, and global cognition, respectively). In longitudinal analyses over 2 years, dominant handgrip strength asymmetry significantly slowed cognitive decline (β = −0.078 and −0.069 for mental status and global cognition, respectively), and non-dominant handgrip strength asymmetry accelerated cognitive decline (β = 0.053 and 0.043 for episodic memory and global cognition, respectively). Weakness was associated with poorer cognitive function at baseline and cognitive decline over 2, 4, and 7 years (all P < 0.05).
In middle-aged and older adults, non-dominant handgrip strength asymmetry and weakness were associated with poorer cognitive function and predicted accelerated cognitive decline. Dominant handgrip strength asymmetry may be beneficial for maintaining cognitive function.</description><identifier>ISSN: 0378-5122</identifier><identifier>ISSN: 1873-4111</identifier><identifier>EISSN: 1873-4111</identifier><identifier>DOI: 10.1016/j.maturitas.2024.108057</identifier><identifier>PMID: 38908060</identifier><language>eng</language><publisher>Ireland: Elsevier B.V</publisher><subject>Aged ; China - epidemiology ; Cognition ; Cognitive Dysfunction - physiopathology ; Cohort Studies ; Female ; Functional laterality ; Hand Strength ; Humans ; Longitudinal Studies ; Male ; Memory, Episodic ; Middle Aged ; Middle-aged adults ; Muscle strength ; Muscle Weakness - physiopathology ; Older adults</subject><ispartof>Maturitas, 2024-09, Vol.187, p.108057, Article 108057</ispartof><rights>2024 Elsevier B.V.</rights><rights>Copyright © 2024 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c247t-e3da14525b92dbbf44dcd911cc0df7421b64140b586900d0bbb71978b0d227353</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.maturitas.2024.108057$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,45974</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38908060$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Youyou</creatorcontrib><creatorcontrib>Zhu, Rui</creatorcontrib><creatorcontrib>Ge, Liru</creatorcontrib><creatorcontrib>Zhang, Xiaoyue</creatorcontrib><creatorcontrib>Tian, Dalong</creatorcontrib><creatorcontrib>Pan, Faming</creatorcontrib><creatorcontrib>Wang, Mengmeng</creatorcontrib><creatorcontrib>Cai, Guoqi</creatorcontrib><title>Association of handgrip strength asymmetry and weakness with cognitive function: a nationally representative cohort study</title><title>Maturitas</title><addtitle>Maturitas</addtitle><description>•Handgrip strength asymmetry with the non-dominant hand having a higher value than the dominant hand predicted accelerated cognitive decline.•Handgrip strength asymmetry with the dominant hand having a higher value than the non-dominant hand was beneficial for cognitive function.•Handgrip weakness predicted accelerated cognitive decline.•Handgrip strength asymmetry may be used to monitor cognitive impairment.
To describe the association of handgrip strength asymmetry and weakness with cognitive function among Chinese middle-aged and older adults.
We used data from four waves (2011, 2013, 2015, and 2018) of the China Health and Retirement Longitudinal Study. Handgrip strength was measured at baseline. Handgrip strength asymmetry was defined on the basis of the ratio of handgrip strength of the non-dominant hand to that of the dominant hand (i.e. non-dominant/dominant): a ratio of <0.9 defined as dominant handgrip strength asymmetry and >1.1 as non-dominant handgrip strength asymmetry. Weakness was defined as a handgrip strength of <28 kg for males or <18 kg for females.
Cognitive function with its two core dimensions (episodic memory and mental status) at each wave was assessed and standardized.
9333 participants (48.3 % female, age 58.2 ± 9.0 years) were included. Non-dominant but not dominant handgrip strength asymmetry was significantly associated with poorer cognitive function at baseline (β = −0.121, −0.092, and −0.132 for mental status, episodic memory, and global cognition, respectively). In longitudinal analyses over 2 years, dominant handgrip strength asymmetry significantly slowed cognitive decline (β = −0.078 and −0.069 for mental status and global cognition, respectively), and non-dominant handgrip strength asymmetry accelerated cognitive decline (β = 0.053 and 0.043 for episodic memory and global cognition, respectively). Weakness was associated with poorer cognitive function at baseline and cognitive decline over 2, 4, and 7 years (all P < 0.05).
In middle-aged and older adults, non-dominant handgrip strength asymmetry and weakness were associated with poorer cognitive function and predicted accelerated cognitive decline. Dominant handgrip strength asymmetry may be beneficial for maintaining cognitive function.</description><subject>Aged</subject><subject>China - epidemiology</subject><subject>Cognition</subject><subject>Cognitive Dysfunction - physiopathology</subject><subject>Cohort Studies</subject><subject>Female</subject><subject>Functional laterality</subject><subject>Hand Strength</subject><subject>Humans</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Memory, Episodic</subject><subject>Middle Aged</subject><subject>Middle-aged adults</subject><subject>Muscle strength</subject><subject>Muscle Weakness - physiopathology</subject><subject>Older adults</subject><issn>0378-5122</issn><issn>1873-4111</issn><issn>1873-4111</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1v1DAQhi0EokvhL4CPXLL4K3HCbVWVD6kSFzhb_pjseknsxXZa5d_j7ZZeOY0088w7mgehD5RsKaHdp-N21mVJvui8ZYSJ2u1JK1-gDe0lbwSl9CXaEC77pqWMXaE3OR8JIS3h4jW64v1Q-Y5s0LrLOVqvi48BxxEfdHD75E84lwRhXw5Y53WeoaQV1xF-AP07QM74wdeZjfvgi78HPC7BnjM-Y43DY5qephUnOCXIEIp-pGw8xFRq9uLWt-jVqKcM757qNfr15fbnzbfm7sfX7ze7u8YyIUsD3GkqWtaagTljRiGcdQOl1hI3SsGo6QQVxLR9NxDiiDFG0kH2hjjGJG_5Nfp4yT2l-GeBXNTss4Vp0gHikhUnkrKedYJXVF5Qm2LOCUZ1Sn7WaVWUqLN3dVTP3tXZu7p4r5vvn44sZgb3vPdPdAV2FwDqq_ceksrWQ7DgfAJblIv-v0f-Ajs4m58</recordid><startdate>202409</startdate><enddate>202409</enddate><creator>Zhang, Youyou</creator><creator>Zhu, Rui</creator><creator>Ge, Liru</creator><creator>Zhang, Xiaoyue</creator><creator>Tian, Dalong</creator><creator>Pan, Faming</creator><creator>Wang, Mengmeng</creator><creator>Cai, Guoqi</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202409</creationdate><title>Association of handgrip strength asymmetry and weakness with cognitive function: a nationally representative cohort study</title><author>Zhang, Youyou ; Zhu, Rui ; Ge, Liru ; Zhang, Xiaoyue ; Tian, Dalong ; Pan, Faming ; Wang, Mengmeng ; Cai, Guoqi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c247t-e3da14525b92dbbf44dcd911cc0df7421b64140b586900d0bbb71978b0d227353</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Aged</topic><topic>China - epidemiology</topic><topic>Cognition</topic><topic>Cognitive Dysfunction - physiopathology</topic><topic>Cohort Studies</topic><topic>Female</topic><topic>Functional laterality</topic><topic>Hand Strength</topic><topic>Humans</topic><topic>Longitudinal Studies</topic><topic>Male</topic><topic>Memory, Episodic</topic><topic>Middle Aged</topic><topic>Middle-aged adults</topic><topic>Muscle strength</topic><topic>Muscle Weakness - physiopathology</topic><topic>Older adults</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Youyou</creatorcontrib><creatorcontrib>Zhu, Rui</creatorcontrib><creatorcontrib>Ge, Liru</creatorcontrib><creatorcontrib>Zhang, Xiaoyue</creatorcontrib><creatorcontrib>Tian, Dalong</creatorcontrib><creatorcontrib>Pan, Faming</creatorcontrib><creatorcontrib>Wang, Mengmeng</creatorcontrib><creatorcontrib>Cai, Guoqi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Maturitas</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Youyou</au><au>Zhu, Rui</au><au>Ge, Liru</au><au>Zhang, Xiaoyue</au><au>Tian, Dalong</au><au>Pan, Faming</au><au>Wang, Mengmeng</au><au>Cai, Guoqi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association of handgrip strength asymmetry and weakness with cognitive function: a nationally representative cohort study</atitle><jtitle>Maturitas</jtitle><addtitle>Maturitas</addtitle><date>2024-09</date><risdate>2024</risdate><volume>187</volume><spage>108057</spage><pages>108057-</pages><artnum>108057</artnum><issn>0378-5122</issn><issn>1873-4111</issn><eissn>1873-4111</eissn><abstract>•Handgrip strength asymmetry with the non-dominant hand having a higher value than the dominant hand predicted accelerated cognitive decline.•Handgrip strength asymmetry with the dominant hand having a higher value than the non-dominant hand was beneficial for cognitive function.•Handgrip weakness predicted accelerated cognitive decline.•Handgrip strength asymmetry may be used to monitor cognitive impairment.
To describe the association of handgrip strength asymmetry and weakness with cognitive function among Chinese middle-aged and older adults.
We used data from four waves (2011, 2013, 2015, and 2018) of the China Health and Retirement Longitudinal Study. Handgrip strength was measured at baseline. Handgrip strength asymmetry was defined on the basis of the ratio of handgrip strength of the non-dominant hand to that of the dominant hand (i.e. non-dominant/dominant): a ratio of <0.9 defined as dominant handgrip strength asymmetry and >1.1 as non-dominant handgrip strength asymmetry. Weakness was defined as a handgrip strength of <28 kg for males or <18 kg for females.
Cognitive function with its two core dimensions (episodic memory and mental status) at each wave was assessed and standardized.
9333 participants (48.3 % female, age 58.2 ± 9.0 years) were included. Non-dominant but not dominant handgrip strength asymmetry was significantly associated with poorer cognitive function at baseline (β = −0.121, −0.092, and −0.132 for mental status, episodic memory, and global cognition, respectively). In longitudinal analyses over 2 years, dominant handgrip strength asymmetry significantly slowed cognitive decline (β = −0.078 and −0.069 for mental status and global cognition, respectively), and non-dominant handgrip strength asymmetry accelerated cognitive decline (β = 0.053 and 0.043 for episodic memory and global cognition, respectively). Weakness was associated with poorer cognitive function at baseline and cognitive decline over 2, 4, and 7 years (all P < 0.05).
In middle-aged and older adults, non-dominant handgrip strength asymmetry and weakness were associated with poorer cognitive function and predicted accelerated cognitive decline. Dominant handgrip strength asymmetry may be beneficial for maintaining cognitive function.</abstract><cop>Ireland</cop><pub>Elsevier B.V</pub><pmid>38908060</pmid><doi>10.1016/j.maturitas.2024.108057</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0378-5122 |
| ispartof | Maturitas, 2024-09, Vol.187, p.108057, Article 108057 |
| issn | 0378-5122 1873-4111 1873-4111 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_3071282643 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Aged China - epidemiology Cognition Cognitive Dysfunction - physiopathology Cohort Studies Female Functional laterality Hand Strength Humans Longitudinal Studies Male Memory, Episodic Middle Aged Middle-aged adults Muscle strength Muscle Weakness - physiopathology Older adults |
| title | Association of handgrip strength asymmetry and weakness with cognitive function: a nationally representative cohort study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T14%3A50%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Association%20of%20handgrip%20strength%20asymmetry%20and%20weakness%20with%20cognitive%20function:%20a%20nationally%20representative%20cohort%20study&rft.jtitle=Maturitas&rft.au=Zhang,%20Youyou&rft.date=2024-09&rft.volume=187&rft.spage=108057&rft.pages=108057-&rft.artnum=108057&rft.issn=0378-5122&rft.eissn=1873-4111&rft_id=info:doi/10.1016/j.maturitas.2024.108057&rft_dat=%3Cproquest_cross%3E3071282643%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3071282643&rft_id=info:pmid/38908060&rft_els_id=S037851222400152X&rfr_iscdi=true |