Lysine methyltransferase 2 plays a key role in the encystation process in the parasite Giardia lamblia

•Wild type cells show an upregulation of lysine methyltransferase-2 during encystation.•Downregulation of lysine methyltransferases-2 prevents encystation and cyst formation.•Interplay of deacetylases and methyltransferases highlights encystation's complexity. Histone post-translational modific...

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Veröffentlicht in:	Acta tropica 2024-09, Vol.257, p.107295, Article 107295
Hauptverfasser:	Díaz-Pérez, Luciano, Salusso, Agostina, Patolsky, Rocío, Mayol, Gonzalo, Quassollo, Gonzalo, Feliziani, Constanza, Touz, María Carolina, Rópolo, Andrea S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cysts Epigenetics Giardia lamblia Giardia lamblia - enzymology Giardia lamblia - genetics Giardia lamblia - growth & development Giardia lamblia - physiology Histone-Lysine N-Methyltransferase - genetics Histone-Lysine N-Methyltransferase - metabolism Lysine methyltransferase 2 Methylation Parasite Encystment - genetics Parasite Encystment - physiology Protein Processing, Post-Translational Protozoan Proteins - genetics Protozoan Proteins - metabolism
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