Coordinated action of a gut–liver pathway drives alcohol detoxification and consumption

Alcohol use disorder (AUD) affects millions of people worldwide, causing extensive morbidity and mortality with limited pharmacological treatments. The liver is considered as the principal site for the detoxification of ethanol metabolite, acetaldehyde (AcH), by aldehyde dehydrogenase 2 (ALDH2) and...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nature metabolism 2024-07, Vol.6 (7), p.1380-1396
Hauptverfasser:	Fu, Yaojie, Mackowiak, Bryan, Lin, Yu-Hong, Maccioni, Luca, Lehner, Taylor, Pan, Hongna, Guan, Yukun, Godlewski, Grzegorz, Lu, Hongkun, Chen, Cheng, Wei, Shoupeng, Feng, Dechun, Paloczi, Janos, Zhou, Huiping, Pacher, Pal, Zhang, Li, Kunos, George, Gao, Bin
Format:	Artikel
Sprache:	eng
Schlagworte:	631/443/319 692/4020/2741 692/4020/4021 692/4020/4021/288 Biomedical and Life Sciences Life Sciences
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!