A Rare Case of Metastatic Spiradenocarcinoma With CDKN2A Mutation
Spiradenocarcinomas are rare malignant skin adnexal tumors. We describe a novel case of a patient with an aggressive CDKN2A-mutated spiradenocarcinoma who responded to a CDK4/6 inhibitor. This case highlights the unique nature of spiradenocarcinomas as well as the potential benefit of targeted thera...
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| Veröffentlicht in: | Oncology (Williston Park, N.Y.) N.Y.), 2024-06, Vol.38 (6), p.230-231 |
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| container_title | Oncology (Williston Park, N.Y.) |
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| creator | Trinh, Jonathan Q Banskota, Shristi Upadhyay Marr, Alissa S |
| description | Spiradenocarcinomas are rare malignant skin adnexal tumors. We describe a novel case of a patient with an aggressive CDKN2A-mutated spiradenocarcinoma who responded to a CDK4/6 inhibitor. This case highlights the unique nature of spiradenocarcinomas as well as the potential benefit of targeted therapy. |
| doi_str_mv | 10.46883/2024.25921022 |
| format | Article |
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We describe a novel case of a patient with an aggressive CDKN2A-mutated spiradenocarcinoma who responded to a CDK4/6 inhibitor. This case highlights the unique nature of spiradenocarcinomas as well as the potential benefit of targeted therapy.</abstract><cop>United States</cop><pub>Intellisphere, LLC</pub><pmid>38899982</pmid><doi>10.46883/2024.25921022</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0890-9091 |
| ispartof | Oncology (Williston Park, N.Y.), 2024-06, Vol.38 (6), p.230-231 |
| issn | 0890-9091 |
| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adenocarcinoma - drug therapy Adenocarcinoma - genetics Adenocarcinoma - pathology Biopsy Cancer therapies Cell cycle Chemotherapy Cyclin-Dependent Kinase 4 - genetics Cyclin-Dependent Kinase 6 - antagonists & inhibitors Cyclin-Dependent Kinase 6 - genetics Cyclin-Dependent Kinase Inhibitor p16 - genetics Dissection Female Genetic aspects Humans Literature reviews Lymphatic system Male Medical imaging Metastasis Middle Aged Mutation Pathology Pemetrexed Piperazines - therapeutic use Protein Kinase Inhibitors - therapeutic use Pulmonary arteries Pyridines - therapeutic use Radiation Skin Neoplasms - drug therapy Skin Neoplasms - genetics Skin Neoplasms - pathology Sweat Gland Neoplasms - drug therapy Sweat Gland Neoplasms - genetics Sweat Gland Neoplasms - pathology |
| title | A Rare Case of Metastatic Spiradenocarcinoma With CDKN2A Mutation |
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